Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan School of Medicine, 1500 East Medical Center Drive, CVC Suite 2364, Ann Arbor, MI 48109-5853, USA.
Cardiol Clin. 2021 Feb;39(1):143-150. doi: 10.1016/j.ccl.2020.09.009. Epub 2020 Oct 29.
Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac condition and highly heterogeneous. Echocardiography and genetic and clinical screening have led to detection in women of childbearing age. Maternal and fetal outcomes among women with HCM are favorable. Genetic counseling is recommended. Prepregnancy clinical evaluation and risk assessment are paramount in ensuring optimal outcomes. Most women carry moderate risk of morbidity, have clinical evaluations and echocardiography each trimester, and deliver vaginally. Those who are symptomatic or have significant left ventricular outflow obstruction or recurrent arrhythmias prior to pregnancy are at higher risk and should be monitored at least monthly.
肥厚型心肌病（HCM）是最常见的遗传性心脏病，具有高度异质性。超声心动图、基因和临床筛查已经导致生育年龄的女性能够被检出。患有 HCM 的女性的母婴结局是良好的。建议进行遗传咨询。妊娠前的临床评估和风险评估对于确保最佳结局至关重要。大多数女性的发病风险中等，每三个月进行一次临床评估和超声心动图检查，并经阴道分娩。那些在妊娠前有症状或有显著左心室流出道梗阻或复发性心律失常的患者风险更高，应至少每月监测一次。
