Zhang Shuai, Shen Yaoyao, Zhou Chenguang, Zhu Weisheng, Zhang Fuqiang, Hu Jie, Liu Dong, Lv Ming
Department of Neurosurgery, Beijing Jingmei Group General Hospital, Beijing 102300, PR China.
Department of Neurology, The Affiliated Hospital of Jiujiang University, Jiujiang 332000, Jiangxi Province, PR China.
J Clin Neurosci. 2020 Nov;81:252-258. doi: 10.1016/j.jocn.2020.09.060. Epub 2020 Oct 16.
To assess the relationship between sleep duration and risk of rupture of intracranial aneurysms (IAs).
According to our inclusion and exclusion criteria, 683 patients admitted to Beijing Tiantan Hospital were included in this study. There were 201 patients in the ruptured group and 482 patients in the unruptured group. Sleep duration was divided into three levels: ≥8 h (long), 6-8 h (normal), ≤6 h (short). Correlation between different sleep duration and rupture of IAs was evaluated by univariate and multivariate regression analysis.
The results of multivariate analysis demonstrated that there was a statistical difference between sleep duration of ≤6 h and sleep duration ≥8 h (OR = 1.76, CI = [1.08-2.87], p = 0.025). There was no statistically significant difference between the group with sleep duration of 6-8 h and sleep duration of ≥8 h (OR = 1.04, CI = [0.65-1.67], p = 0.857).
Short sleep duration (≤6 h) may be related to the rupture of intracranial aneurysms. The reason for this correlation is not yet clear. We suspect that it may be caused by a series of physiological changes caused by reduced sleep.
评估睡眠时间与颅内动脉瘤（IA）破裂风险之间的关系。
根据我们的纳入和排除标准，本研究纳入了683例北京天坛医院收治的患者。破裂组有201例患者，未破裂组有482例患者。睡眠时间分为三个水平：≥8小时（长）、6 - 8小时（正常）、≤6小时（短）。通过单因素和多因素回归分析评估不同睡眠时间与IA破裂之间的相关性。
多因素分析结果显示，睡眠时间≤6小时与睡眠时间≥8小时之间存在统计学差异（OR = 1.76，CI = [1.08 - 2.87]，p = 0.025）。睡眠时间为6 - 8小时的组与睡眠时间≥8小时的组之间无统计学显著差异（OR = 1.04，CI = [0.65 - 1.67]，p = 0.857）。
短睡眠时间（≤6小时）可能与颅内动脉瘤破裂有关。这种相关性的原因尚不清楚。我们怀疑这可能是由睡眠减少引起的一系列生理变化所致。
