Rehabilitation Unit, Kyoto University Hospital, Japan.
Rehabilitation Unit, Kyoto University Hospital, Japan.
J Clin Neurosci. 2020 Nov;81:279-283. doi: 10.1016/j.jocn.2020.09.067. Epub 2020 Oct 16.
An understanding of the dose-response during training is important to identify the rehabilitation programs to obtain the improvement in chronic stroke patients. The purpose of this study was to determine whether distance-dose (distance walked across all sessions) during robot-assisted training affects the change of walking speed and distance in chronic stroke patients after intervention. Fifteen chronic stroke patients were enrolled in this study. The patients performed 8 gait training sessions using the Hybrid Assistive Limb (HAL) for 3 weeks. Gait speed, stride length, cadence, and 2-minute walk test (2MWT) were measured before and post-intervention. Total walking distance (distance walked across all sessions) in individual patients were also measured. Gait speed, stride length, cadence, and 2-minute walk test (2MWT) improved significantly after training. The average of walking distance for 8 sessions in individual patients was 3793.3 ± 2105.3 m. Moreover, the change of gait speed (r = 0.53) and 2MWT (r = 0.70) were positively correlated with the walking distance during 8 sessions. This study of finding demonstrated that greater total distance walked over all sessions of training using the HAL is directly associated with the better walking outcomes in patients with chronic stroke. Further researches with a larger number of patients and a control group are needed to quantify the study results more precisely.
了解训练过程中的剂量反应对于确定康复方案以改善慢性中风患者的状况非常重要。本研究的目的是确定机器人辅助训练过程中的距离剂量(所有训练阶段的行走距离)是否会影响慢性中风患者干预后的步行速度和距离的变化。本研究纳入了 15 名慢性中风患者。患者在 3 周内使用 Hybrid Assistive Limb(HAL)进行了 8 次步态训练。在干预前后测量了步行速度、步长、步频和 2 分钟步行测试(2MWT)。还测量了每位患者在所有训练阶段的总行走距离。训练后,步行速度、步长、步频和 2 分钟步行测试(2MWT)均显著提高。每位患者 8 次训练的平均行走距离为 3793.3±2105.3m。此外,步态速度(r=0.53)和 2MWT(r=0.70)的变化与 8 次训练中的行走距离呈正相关。这项研究表明,使用 HAL 进行的所有训练阶段中行走的总距离越大,与慢性中风患者的步行效果改善程度直接相关。需要进行更多的研究,纳入更多的患者和对照组,以更精确地量化研究结果。