Department of Neuroscience, Yeditepe University, İstanbul, Turkey.
Department of Biostatistics, Uskudar University, İstanbul, Turkey.
J Clin Neurosci. 2020 Nov;81:316-320. doi: 10.1016/j.jocn.2020.09.071. Epub 2020 Oct 20.
Anxiety is commonly observed together with skin diseases and can aggravate them, while skin diseases can increase anxiety. The relationship of skin diseases observed in panic disorder with quantitative electroencephalography (QEEG) findings has not been investigated yet. The aim of this study is to compare the absolute alpha and delta power of panic disorder patients with and without skin disease.
246 panic disorder patients, 19 of whom had skin disease and 227 of whom did not have skin disease, were included in the study. Panic disorder severity scale (PDSS) scores of patients were recorded, and QEEG recording was performed. Absolute alpha and delta power and PDSS scores were compared between the two groups.
It was found that the absolute delta power in the left hemisphere was lower and PDSS scores were higher in the patients with skin diseases compared to the control group. In the patients with skin disease, decreased delta power in the left hemisphere may cause impairment in the processing of positive emotions and may cause trait anxiety.
Trait anxiety may increase susceptibility to skin diseases by disrupting cutaneous homeostasis resulting from the prolonged sympathetic nervous system activation.
焦虑症常与皮肤病同时发生，并可加重皮肤病，而皮肤病也可增加焦虑症。惊恐障碍患者的皮肤病与定量脑电图（QEEG）结果的关系尚未得到研究。本研究旨在比较伴或不伴皮肤病的惊恐障碍患者的绝对α和δ功率。
纳入了 246 例惊恐障碍患者，其中 19 例有皮肤病，227 例无皮肤病。记录患者的惊恐障碍严重程度量表（PDSS）评分，并进行 QEEG 记录。比较两组之间的绝对α和δ功率和 PDSS 评分。
发现与对照组相比，伴皮肤病的患者左半球的绝对δ功率较低，PDSS 评分较高。在患有皮肤病的患者中，左半球的δ功率降低可能导致对正性情绪的处理受损，并可能导致特质性焦虑。
由于长期的交感神经系统激活导致皮肤稳态失调，特质性焦虑可能会增加患皮肤病的易感性。
