Klatsky A L
Department of Medicine, Kaiser Permanente Medical Center, Oakland, California.
Alcohol Alcohol Suppl. 1987;1:117-24.
The central fact about the relations of alcohol consumption to cardiovascular (CV) conditions is disparity. There is powerful evidence that susceptible persons suffer heart muscle damage from use of large amounts of alcoholic beverages, leading to alcoholic cardiomyopathy. Thiamine deficiency has CV consequences which may interact with heavy drinking in persons with poor nutritional intake. Substantial evidence links alcohol use to hypertension. Intervention studies demonstrate an apparent pressor effect of alcohol, which appears and regresses within several days. Alcohol use is inversely related to coronary heart disease (CAD); possible protective mechanisms have surfaced. The data provide no evidence which justify heavier alcohol intake.
饮酒与心血管疾病（CV）之间关系的核心事实是存在差异。有强有力的证据表明，易感人群因大量饮用酒精饮料而遭受心肌损伤，进而导致酒精性心肌病。硫胺素缺乏会产生心血管方面的后果，这可能与营养摄入不良者的大量饮酒相互作用。大量证据将饮酒与高血压联系起来。干预研究表明酒精具有明显的升压作用，这种作用在几天内出现并消退。饮酒与冠心病（CAD）呈负相关；可能的保护机制已浮出水面。现有数据没有提供证明应增加饮酒量的证据。
