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卡托普利对原发性雷诺现象患者皮肤血流的影响。

The effect of captopril on cutaneous blood flow in patients with primary Raynaud's phenomenon.

作者信息

Rustin M H, Almond N E, Beacham J A, Brooks R J, Jones D P, Cooke E D, Dowd P M

机构信息

Department of Dermatology, Middlesex Hospital, London, U.K.

出版信息

Br J Dermatol. 1987 Dec;117(6):751-8. doi: 10.1111/j.1365-2133.1987.tb07356.x.

Abstract

Fifteen patients with primary Raynaud's phenomenon received captopril 25 mg or placebo, three times daily for 6 weeks, in a randomized double-blind cross-over study. Compared with placebo, captopril produced a significant improvement in cutaneous blood flow but did not alter the frequency or severity of attacks of Raynaud's phenomenon.

摘要

在一项随机双盲交叉研究中,15名原发性雷诺现象患者接受了卡托普利25毫克或安慰剂治疗,每日三次,持续6周。与安慰剂相比,卡托普利使皮肤血流量有显著改善,但并未改变雷诺现象发作的频率或严重程度。

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