Department of Cardiovascular Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
Department of Internal Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.
J Card Surg. 2021 Jan;36(1):392-395. doi: 10.1111/jocs.15163. Epub 2020 Nov 22.
Ventricular septal ruptures are an uncommon complication following acute myocardial infarction. Operative repair, utilizing a patch for closure of the defect, is the primary treatment modality to achieve hemodynamic stability. The use of an extracellular matrix derived from small intestinal submucosa as a scaffold for tissue repair is becoming increasingly common. Here, we present the case of a 58-year-old female found to have a ventricular septal rupture and posterior left ventricular aneurysm following late presentation after a myocardial infarction that required operative repair with a CorMatrix patch. Upon readmission for dyspnea and poor exercise tolerance several months later, the patch was subsequently found to have near-completely reabsorbed. There is a paucity of long-term outcomes data following the use of CorMatrix for septal defects, with rare reports of such reabsorption. Further study is required to identify the incidence and implications of such findings.
室间隔破裂是急性心肌梗死后的一种罕见并发症。手术修复，利用补丁封闭缺陷，是实现血液动力学稳定的主要治疗方式。使用源自小肠黏膜下层的细胞外基质作为组织修复的支架越来越常见。在这里，我们介绍了一位 58 岁女性的病例，她在心肌梗死后出现迟发性表现，发现室间隔破裂和左心室后下壁瘤，需要用 CorMatrix 补丁进行手术修复。几个月后因呼吸困难和运动耐量差再次入院，随后发现补丁几乎完全吸收。使用 CorMatrix 修补室间隔缺损的长期结果数据很少，关于这种吸收的报道也很少。需要进一步研究以确定这种发现的发生率和影响。
