内镜超声引导下乙醇消融术治疗有症状的胰腺胰岛素瘤
Endoscopic ultrasound-guided ethanol ablation for the management of a symptomatic pancreatic insulinoma.
作者信息
Mosquera-Klinger Gabriel, Carvajal Jhon Jaime
机构信息
Gastroenterología y Endoscopia Digestiva, Hospital Pablo Tobón Uribe, COLOMBIA.
Gastroenterología y Endoscopia Digestiva, Hospital Pablo Tobón Uribe, Colombia.
出版信息
Rev Esp Enferm Dig. 2021 Jan;113(1):48-51. doi: 10.17235/reed.2020.7109/2020.
INTRODUCTION
pancreatic insulinoma is a sporadic, usually benign, frequently solitary tumor that is smaller than 20 mm. When it is functioning, patients present with symptoms of hypoglycemia secondary to insulin hypersecretion. The diagnosis is clinical, with biochemical and radiological confirmation. Surgery is the management of choice, although endoscopic ultrasound-guided ablation is currently being developed.
MATERIAL AND METHODS
we present a prospective case series of pancreatic insulinoma patients with symptoms of severe hypoglycemia, who were treated with endoscopic ultrasound-guided ethanol ablation as an alternative to surgical management.
RESULTS
technical and clinical success was achieved in all cases and there were no complications associated with the procedure.
CONCLUSION
the treatment of symptomatic insulinoma by endoscopic ultrasound-guided ethanol ablation could be a safe and effective alternative to surgical management in non-surgical patients or those who refuse surgery.
引言
胰腺胰岛素瘤是一种散发性肿瘤，通常为良性，多为单发，直径小于20毫米。当肿瘤具有功能时，患者会出现因胰岛素分泌过多继发的低血糖症状。诊断基于临床症状，并通过生化及影像学检查加以证实。手术是首选的治疗方法，不过目前正在研发内镜超声引导下的消融治疗。
材料与方法
我们报道了一组前瞻性病例，这些胰腺胰岛素瘤患者有严重低血糖症状，接受了内镜超声引导下乙醇消融治疗，作为手术治疗的替代方案。
结果
所有病例均取得了技术及临床成功，且该治疗过程未出现并发症。
结论
对于非手术患者或拒绝手术的患者，内镜超声引导下乙醇消融治疗有症状的胰岛素瘤可能是一种安全有效的手术替代方案。
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