Mittal Ankur, Sarin Indira, Bahuguna Gunjan, Narain Tushar Aditya, Bhirud Deepak Prakash, Ranjan Satish Kumar, Panwar Vikas Kumar
Department of Urology, All India Institute of Medical Sciences, Uttarakhand, India.
Turk J Urol. 2021 Mar;47(2):170-174. doi: 10.5152/tud.2020.20375. Epub 2020 Nov 20.
Surgical treatment for female urethral stricture is varied and lacks consensus. Dorsal and ventral approaches of urethroplasty have comparable success rate with debatable limitations. We describe modifications in dorsal onlay graft urethroplasty to mitigate the surgical limitations and improve functional outcomes.
We retrospectively analyzed 8 patients with strictures treated with dorsal onlay urethroplasty at our center. The inclusion criteria were American Urology Association (AUA) score >20, calibration <14 Fr, positive voiding cystourethrogram, urodynamics with maximum urine flow rate (Qmax) <12 mL/s, detrusor pressure at maximum flow >24 cmHO, and urethroscopic visualization of the stricture. Surgical modifications included dorsal plane dissection away from the clitoris; limited lateral urethral dissection; omitting graft quilting onto the clitoris, and urethral slitting directly at the stricture site (for mid and proximal strictures), sparing the meatus and using canoe-shaped grafts for distal strictures. Success was defined as improvement in the AUA scores and Qmax >12 mL/s, without requiring any further intervention.
The mean age was 50.5±10.6 years. Statistically significant improvements in mean AUA score [14.5±2.20 (p=0.012)], Qmax [23.63±2.44 (p=0.012)], post-void residual urine [107.88±40.37 (p=0.012)], and sexual function scores [6.833±2.23 (p=0.027)] were noted at a mean follow-up of 3 months. Distal strictures were more common. Mean urethral caliber was 9.62 Fr. No cases of de novo incontinence or sexual dissatisfaction were reported.
In our experience, the dorsal onlay technique works well, but without a comparative evidence for ventral onlay, it is difficult to conclude that one is preferred over the other.
女性尿道狭窄的手术治疗方式多样且缺乏共识。尿道成形术的背侧和腹侧入路成功率相当,但存在有争议的局限性。我们描述了背侧镶嵌移植尿道成形术的改良方法,以减轻手术局限性并改善功能结果。
我们回顾性分析了在我们中心接受背侧镶嵌尿道成形术治疗的8例狭窄患者。纳入标准为美国泌尿外科学会(AUA)评分>20、尿道探子校准<14F、排尿性膀胱尿道造影阳性、尿动力学检查最大尿流率(Qmax)<12mL/s、最大尿流时逼尿肌压力>24cmH₂O,以及尿道镜下可见狭窄。手术改良包括远离阴蒂进行背侧平面解剖;有限的尿道外侧解剖;省略移植片缝至阴蒂的操作,对于中近端狭窄直接在狭窄部位切开尿道,保留尿道口,对于远端狭窄使用独木舟形移植片。成功定义为AUA评分改善且Qmax>12mL/s,无需任何进一步干预。
平均年龄为50.5±10.6岁。平均随访3个月时,平均AUA评分[14.5±2.20(p=0.012)]、Qmax[23.63±2.44(p=0.012)]、排尿后残余尿量[107.88±40.37(p=0.012)]和性功能评分[6.833±2.23(p=0.027)]有统计学意义的改善。远端狭窄更常见。平均尿道口径为9.62F。未报告新发尿失禁或性功能不满意病例。
根据我们的经验,背侧镶嵌技术效果良好,但由于缺乏腹侧镶嵌的对比证据,很难得出一种方法优于另一种方法的结论。