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非胰岛素依赖型糖尿病的代谢控制:与患者预后相关的因素

Metabolic control in non-insulin-dependent diabetes mellitus: factors associated with patient outcomes.

作者信息

O'Connor P J, Fragneto R, Coulehan J, Crabtree B F

机构信息

Department of Family Medicine, University of Connecticut/Saint Francis Hospital, Hartford 06105.

出版信息

Diabetes Care. 1987 Nov-Dec;10(6):697-701. doi: 10.2337/diacare.10.6.697.

Abstract

We conducted a cross-sectional study to assess the association of various demographic and medical-care variables with metabolic outcomes in non-insulin-dependent diabetic subjects. The study population was representative of the diagnosed care-seeking diabetic population of a defined geographic community on the Navajo reservation in Arizona. The dependent variable metabolic control was measured as the mean of all random plasma glucose values obtained only at scheduled diabetes clinic visits over 2 yr. Multivariate analysis of the data showed that better metabolic control was most strongly associated with compliance with scheduled appointments. Mode of treatment was also associated with metabolic control. Other variables tested, including source of care, age, sex, duration of diabetes, presence of complications, and weight change, were not associated with metabolic control. The strongest analysis of covariance model with demographic and medical-care variables accounted for 39% of the variance in metabolic control. The analysis suggests that other variables, possibly including several psychosocial variables, need to be assessed for their contribution to metabolic control.

摘要

我们进行了一项横断面研究,以评估各种人口统计学和医疗保健变量与非胰岛素依赖型糖尿病患者代谢结局之间的关联。研究人群代表了亚利桑那州纳瓦霍保留地特定地理社区中已确诊并寻求治疗的糖尿病患者群体。将代谢控制作为因变量,通过仅在两年内定期糖尿病门诊就诊时获得的所有随机血浆葡萄糖值的平均值来衡量。对数据的多变量分析表明,更好的代谢控制与遵守预约就诊的关联最为密切。治疗方式也与代谢控制有关。所测试的其他变量,包括医疗来源、年龄、性别、糖尿病病程、并发症的存在以及体重变化,均与代谢控制无关。包含人口统计学和医疗保健变量的最强协方差分析模型解释了代谢控制中39%的方差。该分析表明,可能需要评估其他变量,或许包括一些心理社会变量,以确定它们对代谢控制的影响。

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