Suppr超能文献

医疗服务不足社区中患者对质子泵抑制剂相关报告不良反应的认知

Patient Awareness of Reported Adverse Effects Associated with Proton Pump Inhibitors in a Medically Underserved Community.

作者信息

White Brian, Drew Matthew, Gaughan John, Phadtare Sangita

机构信息

Department of Biomedical Sciences, Cooper Medical School of Rowan University, 401 S Broadway, Camden, NJ 08103, USA.

Department of Gastroenterology, Cooper University Health Care, 1 Cooper Plaza, Camden, NJ 08103, USA.

出版信息

Healthcare (Basel). 2020 Nov 19;8(4):499. doi: 10.3390/healthcare8040499.

Abstract

Reports of adverse effects associated with proton pump inhibitors (PPIs) are concerning because of high usage and over-the-counter availability. We sought to determine the awareness of PPI adverse effects among our patient population, which is medically underserved, low-income, and racially diverse. A 21-item survey was administered to gastroenterology-clinic outpatients. It collected information about age, gender, education, race, specialty of the prescriber, specific PPI, indication, knowledge of dose, adherence, duration of use and awareness of any risks. Medical records were reviewed to verify survey responses pertaining to indication, dosing, and adherence. A vast majority (96%) of 101 participants were not aware of PPI adverse effects. In total, 63% of the patients completed a high school education or less, which was associated with a higher risk of long-term PPI use than completion of at least an undergraduate degree ( = 0.05). In contrast to other studies, the shockingly low patient awareness about PPI adverse effects in our patient population is particularly concerning, especially as it is tied to their demographic attributes. This may lead to long-term and high-dose PPI use. Our study highlights the need for effective provider-driven education regarding medication risks, especially in the communities with significant health disparities.

摘要

由于质子泵抑制剂(PPI)的高使用量和非处方可得性,与PPI相关的不良反应报告令人担忧。我们试图确定在我们服务不足、低收入且种族多样的患者群体中对PPI不良反应的认知情况。对胃肠病科门诊患者进行了一项包含21个条目的调查。该调查收集了有关年龄、性别、教育程度、种族、开处方者的专业、特定的PPI、适应证、剂量知识、依从性、使用时长以及对任何风险的认知等信息。查阅病历以核实与适应证、剂量和依从性相关的调查回复。101名参与者中的绝大多数(96%)不知道PPI的不良反应。总体而言,63%的患者完成的是高中及以下教育,与至少完成本科学历相比,这与长期使用PPI的风险更高相关(P = 0.05)。与其他研究不同的是,我们患者群体中对PPI不良反应的知晓率低得惊人,这尤其令人担忧,特别是因为这与他们的人口统计学特征相关。这可能导致长期和高剂量使用PPI。我们的研究强调了需要由医疗服务提供者推动进行有效的药物风险教育,特别是在健康差距显著的社区。

相似文献

2
Community-dwelling older adults' awareness of the inappropriate use of proton pump inhibitors.
BMC Geriatr. 2020 Oct 29;20(1):431. doi: 10.1186/s12877-020-01844-w.
3
Patients' Perceptions of Proton Pump Inhibitor Risks and Attempts at Discontinuation: A National Survey.
Am J Gastroenterol. 2019 Feb;114(2):244-249. doi: 10.14309/ajg.0000000000000061.
4
Assessment of Awareness and Knowledge of Proton Pump Inhibitors Among the General Population in Saudi Arabia.
Cureus. 2022 Jul 22;14(7):e27149. doi: 10.7759/cureus.27149. eCollection 2022 Jul.
5
Patients' Knowledge and Pharmacists' Practice Regarding the Long-Term Side Effects of Proton Pump Inhibitors; a Cross-sectional Study.
Arch Acad Emerg Med. 2024 Mar 7;12(1):e35. doi: 10.22037/aaem.v12i1.2305. eCollection 2024.
6
Reported proton pump inhibitor side effects: what are physician and patient perspectives and behaviour patterns?
Aliment Pharmacol Ther. 2020 Jan;51(1):121-128. doi: 10.1111/apt.15522. Epub 2019 Oct 30.
10
Awareness, attitude and behavior regarding proton pump inhibitor among medical staff in the Southwest of China.
BMC Health Serv Res. 2019 Nov 21;19(1):880. doi: 10.1186/s12913-019-4725-6.

引用本文的文献

1
Prevalence and Factors Associated With Proton Pump Inhibitors (PPIs) Use: A Cross-Sectional Study of PERSIAN Guilan Cohort Study.
Health Sci Rep. 2025 Feb 19;8(2):e70494. doi: 10.1002/hsr2.70494. eCollection 2025 Feb.
3
Appropriateness of proton pump inhibitor therapy in an ambulatory geriatrics clinic: A retrospective cross-sectional analysis.
Can Pharm J (Ott). 2023 Oct 11;156(6):331-336. doi: 10.1177/17151635231203214. eCollection 2023 Nov-Dec.
5
Assessment of Awareness and Knowledge of Proton Pump Inhibitors Among the General Population in Saudi Arabia.
Cureus. 2022 Jul 22;14(7):e27149. doi: 10.7759/cureus.27149. eCollection 2022 Jul.

本文引用的文献

1
Increased Risk of COVID-19 Among Users of Proton Pump Inhibitors.
Am J Gastroenterol. 2020 Oct;115(10):1707-1715. doi: 10.14309/ajg.0000000000000798.
2
Racial Disparities-Associated COVID-19 Mortality among Minority Populations in the US.
J Clin Med. 2020 Jul 30;9(8):2442. doi: 10.3390/jcm9082442.
3
Deprescribing Proton Pump Inhibitors in an Academic, Primary Care Clinic: Quality Improvement Project.
J Clin Gastroenterol. 2020 Nov/Dec;54(10):864-870. doi: 10.1097/MCG.0000000000001317.
4
Reported proton pump inhibitor side effects: what are physician and patient perspectives and behaviour patterns?
Aliment Pharmacol Ther. 2020 Jan;51(1):121-128. doi: 10.1111/apt.15522. Epub 2019 Oct 30.
6
The risks of long-term use of proton pump inhibitors: a critical review.
Ther Adv Drug Saf. 2018 Nov 19;10:2042098618809927. doi: 10.1177/2042098618809927. eCollection 2019.
7
Patients' Perceptions of Proton Pump Inhibitor Risks and Attempts at Discontinuation: A National Survey.
Am J Gastroenterol. 2019 Feb;114(2):244-249. doi: 10.14309/ajg.0000000000000061.
9
Patient Values and Preferences Surrounding Proton Pump Inhibitor Use: A Scoping Review.
Patient. 2018 Feb;11(1):17-28. doi: 10.1007/s40271-017-0258-4.
10
Complications of Proton Pump Inhibitor Therapy.
Gastroenterology. 2017 Jul;153(1):35-48. doi: 10.1053/j.gastro.2017.04.047. Epub 2017 May 19.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验