White Brian, Drew Matthew, Gaughan John, Phadtare Sangita
Department of Biomedical Sciences, Cooper Medical School of Rowan University, 401 S Broadway, Camden, NJ 08103, USA.
Department of Gastroenterology, Cooper University Health Care, 1 Cooper Plaza, Camden, NJ 08103, USA.
Healthcare (Basel). 2020 Nov 19;8(4):499. doi: 10.3390/healthcare8040499.
Reports of adverse effects associated with proton pump inhibitors (PPIs) are concerning because of high usage and over-the-counter availability. We sought to determine the awareness of PPI adverse effects among our patient population, which is medically underserved, low-income, and racially diverse. A 21-item survey was administered to gastroenterology-clinic outpatients. It collected information about age, gender, education, race, specialty of the prescriber, specific PPI, indication, knowledge of dose, adherence, duration of use and awareness of any risks. Medical records were reviewed to verify survey responses pertaining to indication, dosing, and adherence. A vast majority (96%) of 101 participants were not aware of PPI adverse effects. In total, 63% of the patients completed a high school education or less, which was associated with a higher risk of long-term PPI use than completion of at least an undergraduate degree ( = 0.05). In contrast to other studies, the shockingly low patient awareness about PPI adverse effects in our patient population is particularly concerning, especially as it is tied to their demographic attributes. This may lead to long-term and high-dose PPI use. Our study highlights the need for effective provider-driven education regarding medication risks, especially in the communities with significant health disparities.
由于质子泵抑制剂(PPI)的高使用量和非处方可得性,与PPI相关的不良反应报告令人担忧。我们试图确定在我们服务不足、低收入且种族多样的患者群体中对PPI不良反应的认知情况。对胃肠病科门诊患者进行了一项包含21个条目的调查。该调查收集了有关年龄、性别、教育程度、种族、开处方者的专业、特定的PPI、适应证、剂量知识、依从性、使用时长以及对任何风险的认知等信息。查阅病历以核实与适应证、剂量和依从性相关的调查回复。101名参与者中的绝大多数(96%)不知道PPI的不良反应。总体而言,63%的患者完成的是高中及以下教育,与至少完成本科学历相比,这与长期使用PPI的风险更高相关(P = 0.05)。与其他研究不同的是,我们患者群体中对PPI不良反应的知晓率低得惊人,这尤其令人担忧,特别是因为这与他们的人口统计学特征相关。这可能导致长期和高剂量使用PPI。我们的研究强调了需要由医疗服务提供者推动进行有效的药物风险教育,特别是在健康差距显著的社区。