Department of Pharmacy, the Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, 646000, China.
Experimental Medicine Center,the Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, 646000, China.
BMC Health Serv Res. 2019 Nov 21;19(1):880. doi: 10.1186/s12913-019-4725-6.
Proton pump inhibitors (PPIs) are one of the most frequently prescribed classes of drug in the world and there is a growing number of publications on correct versus incorrect use of PPIs worldwide. The knowledge of PPIs among the medical staff is essential for improving the rationality of PPI application. The present study aimed to investigate awareness, attitude and behavior toward PPI use among medical staff in the Southwest of China.
The present descriptive-analytical study was conducted on 900 medical staff from three professional groups (300 doctors, 300 nurses and 300 pharmacists) in China. The study data were collected through a self-designed questionnaire which included demographics, awareness, attitude and behavior toward PPI use. The study was carried out in 22 hospitals in Luzhou between February and June 2018.
Of 900 surveys issued, 851valid questionnaires (295doctors, 268 nurses and 288 pharmacists) were returned. Of all respondents, 33.25% were men and 66.75% were women. The score related to PPI awareness score of medical staff was low (59.47 ± 15.75). The level of awareness of pharmacist was significantly higher than that of doctors and nurses (P < 0.01), which was related to gender, age, occupation, educational level, professional title, hospital nature and hospital grade. Similarly, on the attitude towards PPI use, the pharmacists scored also significantly higher than doctors and the nurses (P < 0.01). Three hundred eighty-one of 851 medical staff had used PPI in the past 1 year, of which omeprazole was the most widely used. Among doctors, nurses and pharmacists, the usage rate of PPI was 50.85, 42.16, 40.97%, respectively. The use frequency was related to occupation and professional title. The score about the behavior toward PPIs of the nurses was also significantly lower than that of doctors and pharmacists (P < 0.01).
The study indicated that the medical staff lack of awareness concerning rational use of PPI in China, especially nurse. Thus, it is necessary to call for action on the improvement of PPI awareness and medication-taking behaviors to reduce PPI overuse and to promote the rationality of PPI application.
质子泵抑制剂（PPIs）是世界上使用最广泛的药物之一，全球有越来越多的出版物涉及 PPI 的正确和错误使用。医务人员对 PPI 的了解对于提高 PPI 应用的合理性至关重要。本研究旨在调查中国西南地区医务人员对 PPI 使用的认识、态度和行为。
本描述性分析研究共纳入来自三个专业组（300 名医生、300 名护士和 300 名药剂师）的 900 名医务人员。研究数据通过自设问卷收集，包括人口统计学、对 PPI 使用的认识、态度和行为。该研究于 2018 年 2 月至 6 月在泸州的 22 家医院进行。
共发放 900 份调查问卷，收回 851 份有效问卷（295 名医生、268 名护士和 288 名药剂师）。所有受访者中，男性占 33.25%，女性占 66.75%。医务人员 PPI 认知得分较低（59.47±15.75）。药剂师的 PPI 认知水平明显高于医生和护士（P<0.01），这与性别、年龄、职业、教育水平、职称、医院性质和医院级别有关。同样，在对 PPI 使用的态度方面，药剂师的得分也明显高于医生和护士（P<0.01）。在过去 1 年中，851 名医务人员中有 381 人使用过 PPI，其中奥美拉唑的使用最为广泛。在医生、护士和药剂师中，PPI 的使用率分别为 50.85%、42.16%和 40.97%。使用频率与职业和职称有关。护士对 PPI 行为的评分也明显低于医生和药剂师（P<0.01）。
本研究表明，中国医务人员对 PPI 合理使用的认识不足，特别是护士。因此，有必要采取行动提高医务人员对 PPI 的认识和用药行为，以减少 PPI 的过度使用，促进 PPI 的合理应用。
