Department of Obsterics and Gynecology, Kırıkkale University, Kirikkale, Turkey.
Department of Otolaryngology, Kirikkale University, Kirikkale, Turkey.
J Obstet Gynaecol. 2021 Aug;41(6):939-945. doi: 10.1080/01443615.2020.1819213. Epub 2020 Nov 24.
This cross-sectional study included early menopausal and late menopausal women aged between 40 and 60 years to evaluate the effects of menopause on semicircular canal function. A video head impulse test (vHIT) was performed for all subjects. Vestibulo-ocular reflex (VOR) mean gains of each semicircular canal and gain asymmetry were compared between groups. Of the 87 subjects, 37(42.5%) were reproductive age 28(32.5%) were early menopausal and 22(25.3%) were late menopausal patients. VOR gain of semicircular canals or gain asymmetry values did not differ between groups. In postmenopausal women, presence of vasomotor symptoms was associated with higher gain asymmetry of the left anterior-right posterior (LARP) plane ( = .01), and presence of balance problems was associated with lower right anterior (RA) VOR gain ( = .01). In conclusion semicircular canal function in postmenopausal women was similar to that in women of reproductive age.IMPACT STATEMENT During menopause, women face potential risks such as dizziness, balance problems, falls and fractures. Postmenopausal patients were tested with dynamic posturography to measure balance before and after oestrogen treatment, and it was shown that balance problems significantly improved with oestrogen treatment. Healthy vestibular system is one of the components for sustaining normal balance. In postmenopausal women the function of the semicircular canals is normal and the balance deficit in postmenopausal women may not be caused by the vestibular system. In this study changes within normal limits were observed in vestibular system of postmenopausal women. Reported balance deficits might have been due to central origin. Further research to differentiate origin of balance deficits are needed. Specific research on symptomatic postmenopausal patients would reveal more information.
这项横断面研究纳入了年龄在 40 至 60 岁之间的早绝经和晚绝经女性，以评估绝经对半规管功能的影响。所有受试者均进行视频头脉冲试验（vHIT）。比较各组间各半规管的前庭眼反射（VOR）平均增益和增益不对称性。在 87 名受试者中，37 名（42.5%）处于生育期，28 名（32.5%）为早绝经，22 名（25.3%）为晚绝经患者。各组间半规管 VOR 增益或增益不对称值无差异。在绝经后女性中，血管舒缩症状的存在与左侧前-右侧后（LARP）平面的增益不对称性增加有关（ = .01），平衡问题的存在与右侧前（RA）VOR 增益降低有关（ = .01）。结论：绝经后女性半规管功能与生育期女性相似。
影响说明：在绝经期，女性面临潜在风险，如头晕、平衡问题、跌倒和骨折。对绝经后患者进行动态姿势描记术测试，以测量雌激素治疗前后的平衡，结果表明，平衡问题随着雌激素治疗明显改善。健康的前庭系统是维持正常平衡的组成部分之一。在绝经后女性中，半规管的功能正常，绝经后女性的平衡缺陷可能不是由前庭系统引起的。在这项研究中，绝经后女性的前庭系统观察到了正常范围内的变化。报告的平衡缺陷可能是由于中枢原因。需要进一步研究以区分平衡缺陷的起源。对有症状的绝经后患者进行具体研究将提供更多信息。
