Waldbillig R J, Fletcher R T, Chader G J, Rajagopalan S, Rodrigues M, LeRoith D
Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, Bethesda, MD 20892.
Exp Eye Res. 1987 Dec;45(6):837-44. doi: 10.1016/s0014-4835(87)80100-8.
Bovine retinal rod outer segments (ROS) possess specific, high-affinity receptors for insulin. These receptors exhibit an insulin-stimulatable tyrosine-specific activity that is capable of phosphorylating the receptor's own beta-subunit and exogenous substrate. ROS insulin receptors exhibit heterogeneity in the apparent molecular weight of the receptor's alpha-subunit. In this regard, insulin receptors from this single cell type resemble insulin receptors obtained from whole retina, but are unlike receptors from brain and liver.
牛视网膜视杆细胞外段（ROS）具有胰岛素的特异性高亲和力受体。这些受体表现出胰岛素刺激的酪氨酸特异性活性，能够使受体自身的β亚基和外源性底物磷酸化。ROS胰岛素受体在受体α亚基的表观分子量上表现出异质性。在这方面，来自这种单一细胞类型的胰岛素受体类似于从整个视网膜获得的胰岛素受体，但不同于来自脑和肝脏的受体。
