枕部重复经颅磁刺激不影响多焦视觉诱发电位。
Occipital repetitive transcranial magnetic stimulation does not affect multifocal visual evoked potentials.
机构信息
Department of Neurology, Medical Faculty, Heinrich-Heine University, Moorenstraße 5, 40225, Düsseldorf, Germany.
Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
出版信息
BMC Neurosci. 2020 Nov 23;21(1):48. doi: 10.1186/s12868-020-00600-5.
BACKGROUND
To identify mechanisms of cortical plasticity of the visual cortex and to quantify their significance, sensitive parameters are warranted. In this context, multifocal visual evoked potentials (mfVEPs) can make a valuable contribution as they are not associated with cancellation artifacts and include also the peripheral visual field.
OBJECTIVE
To investigate if occipital repetitive transcranial magnetic stimulation (rTMS) can induce mfVEP changes.
METHODS
18 healthy participants were included in a single-blind crossover-study receiving sessions of excitatory, occipital 10 Hz rTMS and sham stimulation. MfVEP was performed before and after each rTMS session and changes in amplitude and latency between both sessions were compared using generalized estimation equation models.
RESULTS
There was no significant difference in amplitude or latency between verum and sham group.
CONCLUSION
We conclude that occipital 10 Hz rTMS has no effect on mfVEP measures, which is in line with previous studies using full field VEP.
背景
为了确定视觉皮层皮质可塑性的机制，并量化其意义，需要使用敏感的参数。在这种情况下，多焦视觉诱发电位（mfVEP）可以做出有价值的贡献，因为它们与取消伪影无关，并且还包括周边视野。
目的
研究枕叶重复经颅磁刺激（rTMS）是否能引起 mfVEP 的变化。
方法
18 名健康参与者被纳入一项单盲交叉研究，接受兴奋性、枕叶 10 Hz rTMS 和假刺激治疗。在每个 rTMS 疗程前后进行 mfVEP 检查，并使用广义估计方程模型比较两次疗程之间振幅和潜伏期的变化。
结果
真刺激组和假刺激组的振幅或潜伏期没有显著差异。
结论
我们得出结论，枕叶 10 Hz rTMS 对 mfVEP 测量没有影响，这与以前使用全视野 VEP 的研究结果一致。
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