Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Baptist Eye Institute, Kyoto, Japan.
Indian J Ophthalmol. 2020 Dec;68(12):2981-2984. doi: 10.4103/ijo.IJO_1916_19.
To evaluate the long-term contrast sensitivity (CS) after laser in-situ keratomileusis (LASIK) for myopia.
This retrospective, single-center, cohort study involved 190 eyes of 95 patients who underwent bilateral LASIK between January 2001 and October 2007. This study includes patients who underwent CS and higher-order aberration (HOA) measurements in a five-year postoperative period. For all enrolled patients, visual acuity, refractive error (RE) in diopters (D), CS at 3-, 6-, 12-, and 18-cycles per degree (cpd), and HOA in a 4 mm area of the dilated pupil were measured before surgery and 6 months, 1 year, and 5 years after it.
The mean RE measured before the surgery and after 6 months, 1 year, and 5 years after was -6.08 ± 2.50D, -0.26 ± 0.65D, -0.28 ± 0.65D, and -0.48 ± 0.80D, respectively. There were no clinically significant changes between preoperative results and the measures taken 6 months, 1 year, and 5 years after surgery. The slight increase in HOA had little effect on CS over the mid to long-term postoperative period.
Our findings show that CS does not clinically change post LASIK. Although we were unable to identify the specific mechanism, we theorize that after LASIK there is a possibility for the compensation of HOA.
评估近视患者 LASIK 术后的长期对比敏感度（CS）。
这是一项回顾性、单中心、队列研究，共纳入了 95 例患者的 190 只眼，这些患者于 2001 年 1 月至 2007 年 10 月间接受了双眼 LASIK 手术。本研究纳入了在术后 5 年期间接受 CS 和高阶像差（HOA）测量的患者。对于所有入组患者，在术前和术后 6 个月、1 年和 5 年时，测量视力、屈光度（D）的屈光不正（RE）、3、6、12 和 18 周/度（cpd）的 CS 和散瞳后 4mm 区域的 HOA。
术前和术后 6 个月、1 年和 5 年时的平均 RE 分别为-6.08 ± 2.50D、-0.26 ± 0.65D、-0.28 ± 0.65D 和-0.48 ± 0.80D，术后 6 个月、1 年和 5 年时与术前相比均无显著变化。HOA 的轻微增加在中至长期术后对 CS 影响较小。
我们的研究结果表明，LASIK 术后 CS 没有临床变化。虽然我们无法确定具体的机制，但我们推测 LASIK 术后可能存在 HOA 的补偿。
