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Nuclear peroxisome proliferator activated receptor-gamma (PPARγ) as a therapeutic target to treat neurodegeneration and dependence elicited by drugs of abuse.

作者信息

Ciccocioppo Roberto, Ubaldi Massimo

机构信息

School of Pharmacy, Pharmacology Unit, University of Camerino, Camerino, Italy.

出版信息

Neural Regen Res. 2021 May;16(5):984-985. doi: 10.4103/1673-5374.297072.

DOI:10.4103/1673-5374.297072
PMID:33229744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8178789/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e319/8178789/32413c884133/NRR-16-984-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e319/8178789/32413c884133/NRR-16-984-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e319/8178789/32413c884133/NRR-16-984-g001.jpg

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J Neurosci. 2019 Dec 4;39(49):9864-9875. doi: 10.1523/JNEUROSCI.1922-19.2019. Epub 2019 Nov 4.
2
Habenular TCF7L2 links nicotine addiction to diabetes.穹窿 TCF7L2 将尼古丁成瘾与糖尿病联系起来。
Nature. 2019 Oct;574(7778):372-377. doi: 10.1038/s41586-019-1653-x. Epub 2019 Oct 16.
3
Signaling Mechanisms of Selective PPAR Modulators in Alzheimer's Disease.
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Antioxidants (Basel). 2023 Jun 15;12(6):1283. doi: 10.3390/antiox12061283.
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Endocannabinoid-Binding Receptors as Drug Targets.内源性大麻素结合受体作为药物靶点。
Methods Mol Biol. 2023;2576:67-94. doi: 10.1007/978-1-0716-2728-0_6.
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Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism.古柯二醇介导的 JAK/STAT 和 PPAR-γ 调节可预防丙酸诱导的自闭症实验模型中的神经行为和神经化学异常。
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Int J Mol Sci. 2021 Sep 21;22(18):10161. doi: 10.3390/ijms221810161.
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