巴西甘蔗种植工人的肾功能初步评估。
A Preliminary Evaluation of the Kidney Function of Sugarcane Cutters From Brazil.
机构信息
Programa Multicêntrico de Pós-Graduação em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil (Mr Diniz, Mr Canuto, Dr Magalhães, Dr Rocha-Vieira, Dr Amorim); Departamento de Educação Física, Universidade Federal de Juiz de Fora, Governador Valadares, Minas Gerais, Brazil (Dr Machado-Moreira); Fundação Jorge Duprat Figueiredo de Segurança e Medicina do Trabalho, São Paulo, São Paulo, Brazil (Dr Shibuya, Dr da Cunha, Dr Maia, Dr Roscani, Dr Santiago de Moraes Barros, Dr Bitencourt); Faculdade de Ciências Médicas da Santa Casa, São Paulo, São Paulo, Brazil (Dr Souza e Silva de Almeida); University of New Mexico, Albuquerque, New Mexico (Mr McKenna, Dr Amorim).
出版信息
J Occup Environ Med. 2021 Feb 1;63(2):e53-e58. doi: 10.1097/JOM.0000000000002090.
OBJECTIVE
To evaluate clinical parameters, markers of kidney function, and skeletal muscle damage in a group of sugarcane cutters during harvesting season.
METHODS
Seventeen volunteers were assessed for anthropometrics and cardiorespiratory fitness. Blood and urine samples were collected 48-hours after the last work session. Blood was analyzed for glucose, creatine kinase, cholesterol, and a complete hemogram. Urine and blood samples were also analyzed for markers related to kidney function.
RESULTS
Volunteers were young (26 ± 6 y), had low body fat (13 ± 5%), and good cardiorespiratory fitness (41 ± 6 mL/kg/min). Classical markers of kidney function (eGFR, creatinine, cystatin C) were within the normal range. However, ten volunteers presented elevated resting serum creatine kinase (221 ± 68 U/L).
CONCLUSION
Manual sugarcane harvesting is associated with sustained skeletal muscle damage which may increase the risk for kidney injury in Brazilian sugarcane cutters.
目的
评估甘蔗收割季节一组甘蔗工人的临床参数、肾功能标志物和骨骼肌损伤情况。
方法
对 17 名志愿者进行人体测量和心肺功能评估。最后一次工作结束后 48 小时采集血样和尿样。血液分析葡萄糖、肌酸激酶、胆固醇和全血细胞计数。尿液和血液样本也用于分析与肾功能相关的标志物。
结果
志愿者年龄较小（26±6 岁），体脂较低（13±5%），心肺功能良好（41±6 mL/kg/min）。经典的肾功能标志物（eGFR、肌酐、胱抑素 C）均在正常范围内。然而，有 10 名志愿者静息血清肌酸激酶升高（221±68 U/L）。
结论
手工收割甘蔗与持续的骨骼肌损伤有关，这可能会增加巴西甘蔗工人发生肾损伤的风险。
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