Department of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA Leiden, The Netherlands.
Institut Laue-Langevin, 71 Avenue des Martyrs, BP 156, 38042 Grenoble, France.
Langmuir. 2020 Dec 8;36(48):14478-14482. doi: 10.1021/acs.langmuir.0c01691. Epub 2020 Nov 24.
Theoretical simulations have predicted that a lipid bilayer forms a stable superstructure when a sheet of graphene is inserted in its hydrophobic core. We experimentally produced for the first time a lipid-graphene-lipid assembly by combining the Langmuir-Blodgett and the Langmuir-Schaefer methods. Graphene is sandwiched and remains flat within the hydrophobic core of the lipid bilayer. Using infrared spectroscopy, ellipsometry, and neutron reflectometry, we characterized the superstructure at every fabrication step. The hybrid superstructure is mechanically stable and graphene does not disturb the natural lipid bilayer structure.
理论模拟预测，当石墨烯片插入疏水分子核心时，脂质双层会形成稳定的超结构。我们首次通过结合 Langmuir-Blodgett 和 Langmuir-Schaefer 方法，成功制备了脂质-石墨烯-脂质组装体。石墨烯被夹在脂质双层的疏水分子核心内并保持平坦。我们使用红外光谱、椭圆偏振和中子反射技术，在每个制备步骤中对超结构进行了表征。该杂化超结构具有机械稳定性，并且石墨烯不会干扰天然脂质双层结构。
