Malopolska Centre of Food Monitoring, Faculty of Food Technology, University of Agriculture in Krakow, Balicka St. 122, 30-149 Krakow, Poland.
Malopolska Centre of Food Monitoring, Faculty of Food Technology, University of Agriculture in Krakow, Balicka St. 122, 30-149 Krakow, Poland.
Food Res Int. 2020 Nov;137:109583. doi: 10.1016/j.foodres.2020.109583. Epub 2020 Jul 23.
Per- and polyfluoroalkyl substances (PFASs) are man-made chemicals that have been identified as global pollutants. Their widespread occurrence, including in food, is a potential concern for consumers. This work focuses on the application of a simple and reliable analytical method for the simultaneous determination of ten perfluoroalkyl acids in highly complex fatty matrices (fats and oils). The perfluoroalkyl substances were extracted by the QuEChERS method, based on the dispersive-Solid Phase Extraction using styrene-divinylbenzene bulk sorbent, and quantitatively analysed by micro-high performance liquid chromatography tandem mass spectrometry. Recoveries ranged from 72 to 104% with an acceptable relative standard deviation below 10%. Limits of quantification were within the range 0.002-0.075 ng/g depending on the perfluoroalkyl compound. The most predominant compound in fat and oil food samples was perfluorooctanoic acid (PFOA) with a detection frequency of 100%, and the highest levels were found for perfluorobutanoic acid (PFBA). The estimated exposure to PFOA, which was 46% and 19% of the existing TWI for the EU and Polish population, respectively, is relatively high and indicates a potential risk to human health.
全氟和多氟烷基物质（PFASs）是人造化学物质，已被确定为全球性污染物。它们在食品中的广泛存在是消费者关注的潜在问题。本工作重点介绍了一种简单可靠的分析方法，用于同时测定高度复杂的脂肪基质（脂肪和油）中的十种全氟烷基酸。采用 QuEChERS 方法提取全氟烷基物质，基于使用苯乙烯-二乙烯基苯整体吸附剂的分散固相萃取，并用微高效液相色谱串联质谱法进行定量分析。回收率在 72%至 104%之间，相对标准偏差可接受，低于 10%。根据不同的全氟烷基化合物，定量限在 0.002-0.075 ng/g 范围内。在脂肪和油食品样品中，最主要的化合物是全氟辛酸（PFOA），检出率为 100%，含量最高的是全氟丁烷酸（PFBA）。对 PFOA 的估计暴露量分别为欧盟和波兰人群现有 TWI 的 46%和 19%，相对较高，表明对人类健康存在潜在风险。
