Aparato Digestivo, Hospital Clínico San Cecilio, España.
Aparato Digestivo, Hospital Clínico San Cecilio.
Rev Esp Enferm Dig. 2021 Apr;113(4):269-271. doi: 10.17235/reed.2020.7303/2020.
the autonomic dysfunction defines the neuropathy of the autonomic nervous system. The prevalence of the gastric dysmotility and its relationship with the autonomic dysfunction in patients with alcohol chronic liver disease is not well known.
thirty-six patients with alcohol chronic liver disease and 25 healthy controls were evaluated, in order to detect an autonomic dysfunction through different cardiovascular reflexes and gastric emptying tests.
ninety-four per cent of the patients showed an impaired R index (variations in heart rate during six deep inspirations-expirations per minute) and/or S/S-HR (variations in heart rate when standing from a supine position). Seventy-five per cent of the patients showed gastroparesis (T1/2: gastric half-emptying time was delayed). There was a correlation between the R index and T1/2 (r = -0.49; p < 0.01).
we suggest that gastroparesis detected in alcoholic chronic liver disease is another clinical manifestation of the autonomic parasympathetic dysfunction.
自主神经功能障碍定义为自主神经系统的神经病变。胃动力障碍的患病率及其与酒精性慢性肝病患者自主神经功能障碍的关系尚不清楚。
评估了 36 例酒精性慢性肝病患者和 25 例健康对照者，通过不同的心血管反射和胃排空试验来检测自主神经功能障碍。
94%的患者表现出 R 指数（每分钟 6 次深呼吸时心率的变化）和/或 S/S-HR（从仰卧位站立时心率的变化）受损。75%的患者出现胃轻瘫（T1/2：胃排空时间延迟）。R 指数与 T1/2 之间存在相关性（r=-0.49；p<0.01）。
我们认为酒精性慢性肝病中检测到的胃轻瘫是自主副交感神经功能障碍的另一种临床表现。
