Tagliaferri Ariana Rose
Department of Internal Medicine, St. Joseph's University Medical Center, Paterson, NJ, USA.
J Community Hosp Intern Med Perspect. 2020 Sep 3;10(5):456-459. doi: 10.1080/20009666.2020.1796053.
Sarcoidosis is a multisystem disease involving the lungs in up to 90% of cases; however, 30% of patients will have systemic sarcoidosis, including involvement of the heart. Cardiac sarcoidosis can affect any part of the heart and manifest in various ways, with the most common presentations being AV block, arrhythmias, heart failure and sudden cardiac death. Due to the overlap of symptoms and other cardiac diseases, including silent disease, cardiac sarcoidosis is difficult to diagnose. Many cases are underreported. However, due to the nature of the disease, cardiac sarcoidosis can have serious consequences that can be prevented with early intervention. This paper will focus on the challenges in diagnosing cardiac sarcoidosis, how to differentiate cardiac sarcoidosis from other common conditions by detecting subtle clinical differences, and how various investigations and imaging modalities should be used in aiding diagnosis and determining prognostic severity, such that early intervention can be initiated.
结节病是一种多系统疾病，高达90%的病例累及肺部；然而，30%的患者会出现系统性结节病，包括心脏受累。心脏结节病可累及心脏的任何部位，并以多种方式表现出来，最常见的表现是房室传导阻滞、心律失常、心力衰竭和心源性猝死。由于症状与其他心脏疾病（包括无症状疾病）存在重叠，心脏结节病难以诊断。许多病例报告不足。然而，由于该疾病的性质，心脏结节病可能会产生严重后果，早期干预可预防这些后果。本文将重点讨论心脏结节病的诊断挑战、如何通过检测细微的临床差异将心脏结节病与其他常见病症区分开来，以及应如何使用各种检查和成像方式辅助诊断并确定预后严重程度，以便能够尽早开展干预。
