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单侧聋和非对称听力损失的治疗选择。对 155 例患者的前瞻性、多中心队列研究。

Treatment choice in single-sided deafness and asymmetric hearing loss. A prospective, multicentre cohort study on 155 patients.

机构信息

Service d'Otologie, Otoneurologie et ORL Pédiatrique, Hôpital Pierre-Paul Riquet, CHU Toulouse Purpan, France.

Brain & Cognition Research Centre, UMR 5549, Université Toulouse III, France.

出版信息

Clin Otolaryngol. 2021 Jul;46(4):736-743. doi: 10.1111/coa.13672. Epub 2021 Mar 26.

DOI:10.1111/coa.13672
PMID:33236413
Abstract

OBJECTIVES

To describe the treatment choice in a cohort of subjects with single-sided deafness (SSD) and asymmetric hearing loss (AHL). To assess the reliability of the treatment trials.

DESIGN

In this national, multicentre, prospective study, the choice of subjects was made after two consecutive trials of Contralateral Routing Of the Signal (CROS) hearing aids and a Bone Conduction Device (BCD) on a headband. Subjects could proceed with one of these two options, opt for cochlear implantation or decline all treatments.

SETTING

Seven tertiary university hospitals.

PARTICIPANTS

One hundred fifty-five subjects with SSD or AHL fulfilling the candidacy criteria for cochlear implantation, with or without associated tinnitus.

MAIN OUTCOME MEASURES

After the two trials, the number of subjects choosing each option was described. Repeated assessments of both generic and auditory-specific quality of life were conducted, as well as hearing assessments (speech recognition in noise and horizontal localization).

RESULTS

CROS was chosen by 75 subjects, followed by cochlear implantation (n = 51), BCD (n = 18) and abstention (n = 11). Patients who opted for cochlear implantation had a poorer quality of life (P = .03). The improvement of quality of life indices after each trial was significantly associated with the final treatment choice (P = .008 for generic indices, P = .002 for auditory-specific indices). The follow-up showed that this improvement had been overestimated in the CROS group, with a long-term retention rate of 52.5%.

CONCLUSIONS

More than one third of SSD/AHL subjects are unsatisfied after CROS and BCD trials. Repeated quality of life assessments help counselling the patient for his/her treatment choice.

摘要

目的

描述单侧聋(SSD)和非对称听力损失(AHL)患者队列的治疗选择。评估治疗试验的可靠性。

设计

在这项全国性的、多中心的前瞻性研究中,在连续两次对信号对侧转导(CROS)助听器和头戴式骨导装置(BCD)进行试验后,选择了受试者。受试者可以选择这两种方案中的一种,选择进行人工耳蜗植入,或拒绝所有治疗。

地点

七所三级大学医院。

参与者

155 名符合人工耳蜗植入候选标准的 SSD 或 AHL 患者,伴有或不伴有相关耳鸣。

主要观察指标

两次试验后,描述选择每种方案的受试者人数。进行了通用和听觉特异性生活质量的重复评估,以及听力评估(噪声中的言语识别和水平定位)。

结果

75 名受试者选择了 CROS,其次是人工耳蜗植入(n=51)、BCD(n=18)和弃权(n=11)。选择人工耳蜗植入的患者生活质量较差(P=0.03)。每次试验后生活质量指数的改善与最终治疗选择显著相关(P=0.008 用于通用指数,P=0.002 用于听觉特异性指数)。随访显示,CROS 组的改善被高估,长期保留率为 52.5%。

结论

超过三分之一的 SSD/AHL 患者在 CROS 和 BCD 试验后不满意。重复的生活质量评估有助于为患者的治疗选择提供咨询。

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