Humphries J O
Cardiovasc Clin. 1977;8(2):41-54.
It is apparent that coronary artery disease is extremely common. As many as 15 percent of young men have significant disease of at least one major coronary artery. Each year approximately 1 percent of middle aged men will develop symptoms of coronary disease. The standard risk factors identify people with a greater risk of developing symptoms. The overall mortality rate of symptomatic patients is about 4 to 5 percent per year in patients with all types of angina pectoris and in survivors of acute myocardial infarction. In symptomatic patients it is possible to identify groups with a risk a dying as low as 1 percent per year and other groups with a risk of dying of 25 to 50 percent per year by simple, noninvasive techniques. However the most powerful predictors of survival in asymptomatic or symptomatic patients are the severity of the coronary artery disease and damage to the left ventricle.
显然，冠状动脉疾病极为常见。多达15%的年轻男性至少有一条主要冠状动脉患有严重疾病。每年约1%的中年男性会出现冠心病症状。标准风险因素可识别出有更高发病风险的人群。在所有类型心绞痛患者和急性心肌梗死幸存者中，有症状患者的总体死亡率约为每年4%至5%。通过简单的非侵入性技术，在有症状患者中可以识别出每年死亡风险低至1%的群体以及每年死亡风险为25%至50%的其他群体。然而，无症状或有症状患者生存的最有力预测因素是冠状动脉疾病的严重程度和左心室损伤。
