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Roux-en-Y 胃旁路手术治疗高血压和糖尿病的效果。

The effect of Roux-en-Y gastric bypass in the treatment of hypertension and diabetes.

机构信息

- Faculdade de Ciências Médicas da Santa Casa de São Paulo, Medicina - São Paulo - SP - Brasil.

- Universidade Santo Amaro, Pesquisa e Extensão - São Paulo - SP - Brasil.

出版信息

Rev Col Bras Cir. 2020 Nov 23;47:e20202655. doi: 10.1590/0100-6991e-20202655. eCollection 2020.

DOI:10.1590/0100-6991e-20202655
PMID:33237184
Abstract

INTRODUCTION

obesity has become a public health problem in Brazil and worldwide, due to its high prevalence. It is considered a risk factor for systemic arterial hypertension (SAH) and type 2 diabetes mellitus T2DM. Although lifestyle changes can control and even achieve complete T2DM remission, most patients have difficulty controlling blood glucose. Recent studies show that the Roux-en-Y gastric bypass (RYGB) is efficient for weight loss and control of T2DM and SAH in obese individuals.

OBJECTIVE

to analyze the effect of the RYGB technique on the control and treatment of comorbidities related to obesity.

METHOD

this is a retrospective cohort study, with information obtained from the review of medical records, with data collection in the pre and postoperative period of patients undergoing bariatric surgery. We selected those with T2DM and SAH for the study.

RESULTS

252 patients underwent RYGB in the service. Seventy-nine (31.3%) had T2DM and 64 had SAH associated with T2DM. Regarding T2DM and SAH, 37.9% and 43,7%, respectively, showed total remission of the disease after surgery. There was a reduction in the postoperative use of Metformin, insulin / Gliclazide, Propranolol, Losartan and Hydrochlorothiazide in 62%, 10.1%, 100%, 26.5% and 22.8% of patients, respectively.

CONCLUSION

the RYGB technique is effective in the remission of T2DM and SAH. Even in cases where there was no total remission of the diseases, there was a significant drop in the use of medicines used for their treatment.

摘要

简介

肥胖已成为巴西乃至全球的公共卫生问题,其高患病率不容忽视。肥胖被认为是系统性动脉高血压(SAH)和 2 型糖尿病(T2DM)的危险因素。尽管生活方式的改变可以控制甚至完全缓解 T2DM,但大多数患者难以控制血糖。最近的研究表明,Roux-en-Y 胃旁路术(RYGB)在肥胖个体中对减肥和控制 T2DM 和 SAH 有效。

目的

分析 RYGB 技术对肥胖相关合并症的控制和治疗效果。

方法

这是一项回顾性队列研究,通过回顾病历获取信息,在患者接受减重手术后的术前和术后期间进行数据收集。我们选择了那些患有 T2DM 和 SAH 的患者进行研究。

结果

该服务共进行了 252 例 RYGB 手术。79 例(31.3%)患有 T2DM,64 例患有与 T2DM 相关的 SAH。在 T2DM 和 SAH 方面,分别有 37.9%和 43.7%的患者在手术后完全缓解了疾病。术后,分别有 62%、10.1%、100%、26.5%和 22.8%的患者减少了二甲双胍、胰岛素/格列齐特、普萘洛尔、氯沙坦和氢氯噻嗪的使用。

结论

RYGB 技术在 T2DM 和 SAH 的缓解方面有效。即使在疾病没有完全缓解的情况下,用于治疗这些疾病的药物的使用也显著下降。

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