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影响炎症性肠病患者经皮腹腔脓肿引流术累积辐射剂量的因素。

Factors influencing cumulative radiation dose from percutaneous intra-abdominal abscess drainage in the setting of inflammatory bowel disease.

机构信息

Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.

Department of Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1471, Houston, TX, 77030, USA.

出版信息

Abdom Radiol (NY). 2021 May;46(5):2195-2202. doi: 10.1007/s00261-020-02864-1. Epub 2020 Nov 25.

Abstract

PURPOSE

Patients with inflammatory bowel disease (IBD) are at risk for intra-abdominal abscesses requiring CT-guided drainage. These patients are at baseline risk of high cumulative radiation exposure from imaging, which may be exacerbated by CT-guided drainage. This study aimed to determine the radiation dose associated with percutaneous drainage in the setting of IBD and identify risk factors associated with high exposure.

METHODS

An IRB-approved single-center retrospective study was performed to identify patients with IBD who underwent percutaneous abscess drainage over a 5-year period. An episode of drainage was defined from drain placement to removal, with all intervening procedures and diagnostic CT scans included in the cumulative radiation dose.

RESULTS

The mean cumulative effective dose for a drainage episode was 47.50 mSv. The mean duration of a drainage episode was 68.7 days. Patients with a cumulative dose greater than 50 mSv required higher number of follow-up visits compared to patients with less than 50 mSv (6.9 vs. 3.5, p = 0.003*). Patients with higher cumulative dose were also more likely to require drain upsize (54% vs. 13%, p = 0.01*) or additional drain placement (63% vs 24%, p = 0.03*) compared to patients with lower dose.

CONCLUSION

Intra-abdominal abscess drainage may be associated with significant cumulative radiation exposure. Requirement of drain upsizing or additional drain placement were associated with higher cumulative radiation dose, which may be related to more severe underlying inflammatory bowel disease.

摘要

目的

患有炎症性肠病 (IBD) 的患者存在需要 CT 引导引流的腹腔脓肿风险。这些患者在基线时就存在因影像学检查而累积接受大量辐射的风险,而 CT 引导引流可能会使这种风险进一步加剧。本研究旨在确定 IBD 患者经皮引流的辐射剂量,并确定与高暴露相关的危险因素。

方法

进行了一项经过机构审查委员会批准的单中心回顾性研究,以确定在过去 5 年内接受经皮脓肿引流的 IBD 患者。引流的一个阶段定义为从放置引流管到取出引流管的时间段,所有介入程序和诊断性 CT 扫描都包含在累积辐射剂量中。

结果

一次引流的平均累积有效剂量为 47.50 mSv。引流阶段的平均持续时间为 68.7 天。与累积剂量小于 50 mSv 的患者相比,累积剂量大于 50 mSv 的患者需要更多的随访次数(6.9 次比 3.5 次,p=0.003*)。累积剂量较高的患者还更有可能需要增大引流管(54%比 13%,p=0.01*)或额外放置引流管(63%比 24%,p=0.03*),而不是累积剂量较低的患者。

结论

腹腔脓肿引流可能会导致大量的累积辐射暴露。需要增大引流管或额外放置引流管与更高的累积辐射剂量相关,这可能与更严重的潜在炎症性肠病有关。

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