Kannichamy Vishmita, Antony Ishan, Mishra Vinayak, Banerjee Amit, Gandhi Arohi B, Kaleem Ifrah, Alexander Josh, Hisbulla Mohamed, Khan Safeera
Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
General Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Cureus. 2020 Oct 22;12(10):e11096. doi: 10.7759/cureus.11096.
Ulcerative colitis (UC) is primarily a disease of non-smokers or ex-smokers. Since there have been previous claims of the beneficial effects of transdermal nicotine, researchers studied its efficacy to include it in the treatment regimen: to prevent remissions and as maintenance therapy. This review aims to evaluate the efficacy of transdermal nicotine as a treatment option for mild to moderately active ulcerative colitis. We shortlisted 22 articles after a careful analysis and elimination process. These articles were reviewed and analyzed, and it was found that transdermal nicotine in combination with conventional therapy was more beneficial than individual treatment with either. Further controlled studies evaluating the appropriate dosage for remission and maintenance treatment needs to be done.
溃疡性结肠炎（UC）主要是一种非吸烟者或已戒烟者易患的疾病。由于此前有关于经皮尼古丁有益作用的说法，研究人员对其疗效进行了研究，以便将其纳入治疗方案：预防病情缓解和作为维持治疗。本综述旨在评估经皮尼古丁作为轻度至中度活动性溃疡性结肠炎治疗选择的疗效。经过仔细的分析和筛选过程，我们列出了22篇文章。对这些文章进行了审查和分析，发现经皮尼古丁与传统疗法联合使用比单独使用任何一种疗法都更有益。需要进一步进行对照研究，以评估用于缓解和维持治疗的合适剂量。
