Abdi E A, Ding J C, Cooper I A
Haematology Research Unit, Peter MacCallum Hospital, Melbourne, Australia.
Postgrad Med J. 1987 Jun;63(740):455-8. doi: 10.1136/pgmj.63.740.455.
Opportunistic infections are increasingly becoming a problem in cancer patients amongst whom infection with Nocardia species is particularly difficult to detect due to the capricious natural history of the disease. Three cases of Nocardia infection in patients who had undergone splenectomy for haematological malignancy are presented. These cases illustrate the diverse mode of presentation, the natural history and the difficulties in early and accurate diagnosis of Nocardia infection. Despite the difficulties in arriving at the correct diagnosis, these cases highlight the importance of early institution of appropriate antibiotic therapy. Antibiotics should be given in adequate doses to control the initial infection and be maintained for a prolonged period to prevent relapses.
机会性感染在癌症患者中日益成为一个问题，在这些患者中，由于诺卡菌病多变的自然病程，诺卡菌属感染特别难以检测。本文报告了3例因血液系统恶性肿瘤行脾切除术患者发生诺卡菌感染的病例。这些病例说明了诺卡菌感染的多种表现形式、自然病程以及早期准确诊断的困难。尽管难以做出正确诊断，但这些病例凸显了早期给予适当抗生素治疗的重要性。应给予足够剂量的抗生素以控制初始感染，并持续较长时间以预防复发。
