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术后巩膜切除术后浆液性脉络膜脱离是否是远期失败的危险因素。

Is post-trabeculectomy serous choroidal detachment a risk factor for failure in the long term.

机构信息

Basir Eye Health Research Center, Tehran, Iran.

Department of Ophthalmology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Eur J Ophthalmol. 2022 Jan;32(1):282-287. doi: 10.1177/1120672120972626. Epub 2020 Nov 26.

Abstract

BACKGROUND

To investigate the long-term effect of serous choroidal detachment on the success of trabeculectomy in glaucoma patients.

METHODS

In this case-control study, 17 patients who underwent trabeculectomy and developed choroidal detachment, and completed at least 3 years of follow-up were included. The controls were matched based on age, sex, preoperative intraocular pressure, and glaucoma type, and lack of choroidal detachment. Surgical success was defined based on two definitions of 5 < IOP < 16 and 20% reduction from the baseline and no need for further glaucoma surgery and all the same but 5 < IOP < 22.

RESULTS

The mean estimated duration of survival ±SD was 2.73 ± 0.35 years (CI 95% 2.1, 3.4), which was significantly shorter than 3.98 ± 0.38 years (CI 95% 3.3, 4.7) in the control group. (LogRank = 5.03  = 0.02). Cumulative probability of success was 76.5%, 52.9%, 29.4%, 17.6%, and 11.8% in year 1, 2, 3, 4, and 5 in the case group, respectively. Corresponding values were 88.2%, 82.4%, 68.6%, 58.8%, and 47.1%. In the control group, respectively. At baseline, average IOP was 22.3 ± 2.7 and 23.8 ± 8.3 mmHg in the case and control groups, respectively ( = 0.17). Mean IOP was significantly higher in the case group than in the control group in years 2, 3, 4, and 5.

CONCLUSION

Serous choroidal detachment affects the long-term surgical success of trabeculectomy, especially in patients with advanced glaucoma when lower target pressure is required.

摘要

背景

研究在青光眼患者中,脉络膜脱离对小梁切除术成功的长期影响。

方法

在这项病例对照研究中,纳入了 17 名接受小梁切除术并发生脉络膜脱离的患者,这些患者至少完成了 3 年的随访。对照组根据年龄、性别、术前眼压和青光眼类型以及无脉络膜脱离进行匹配。手术成功定义基于两种定义:5<眼压<16mmHg 和从基线水平下降 20%且无需进一步青光眼手术,以及所有相同但 5<眼压<22mmHg。

结果

平均估计生存时间±SD 为 2.73±0.35 年(95%CI 95%为 2.1,3.4),明显短于对照组的 3.98±0.38 年(95%CI 95%为 3.3,4.7)。(对数秩检验 = 5.03, = 0.02)。病例组在第 1、2、3、4 和 5 年的累积成功率分别为 76.5%、52.9%、29.4%、17.6%和 11.8%,对照组分别为 88.2%、82.4%、68.6%、58.8%和 47.1%。在基线时,病例组和对照组的平均眼压分别为 22.3±2.7mmHg 和 23.8±8.3mmHg( = 0.17)。病例组在第 2、3、4 和 5 年的平均眼压明显高于对照组。

结论

脉络膜脱离会影响小梁切除术的长期手术成功率,尤其是在需要较低目标眼压的晚期青光眼患者中。

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