Yadgari Maryam, Shojaei Baghini Ahmad, Vafaei Fatemeh, Attarian Behnoosh, Hatami Mohammadmehdi, Sheibani Kourosh, Hooshmandi Sadid
Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Science, Tehran, Iran.
Basir Eye Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2025 Jan 18;36(2):129-135. doi: 10.4103/joco.joco_245_23. eCollection 2024 Apr-Jun.
To investigate the effect of serous choroidal detachment (SCD) on the success of Ahmed glaucoma valve (AGV) implantation.
Patients who underwent AGV implantation and developed SCD were included in the case group. The control group was matched based on age, sex, baseline intraocular pressure (IOP), glaucoma type, and the number of glaucoma medications. The patient data were retrospectively extracted from available records. The primary outcome measure was an AGV success rate based on 5 < IOP <18 and a 20% reduction from baseline.
Seventeen patients were enrolled in the case group and 38 in the control group. Preoperative visual acuity of patients was 1.17 ± 0.43 and 1.16 ± 0.37 logMAR in the case and control groups, respectively. The patients in the case group showed higher mean IOP at all time intervals compared to controls. However, the mean IOP only reached a statistically significant difference at 3 months (17.94 ± 6.78 mmHg vs. 13.39 ± 3.09 mmHg, = 0.003). The mean survival duration was significantly shorter in patients with SCD (10.4 ± 0.7 months vs. 11.7 ± 0.2 months for controls log-rank = 4.1, = 0.04). The cumulative probability of success was 76.5% in patients with SCD and 94.7% in the control group after 12 months.
SCD after AGV implantation could be a risk factor for failure. A larger prospective study with a longer follow-up duration is required to confirm the present study results.
探讨浆液性脉络膜脱离（SCD）对艾哈迈德青光眼阀（AGV）植入术成功率的影响。
将接受AGV植入术并发生SCD的患者纳入病例组。对照组根据年龄、性别、基线眼压（IOP）、青光眼类型和青光眼药物使用数量进行匹配。从现有记录中回顾性提取患者数据。主要观察指标是基于眼压5＜IOP＜18且较基线降低20%的AGV成功率。
病例组纳入17例患者，对照组纳入38例患者。病例组和对照组患者术前视力分别为1.17±0.43和1.16±0.37 logMAR。病例组患者在所有时间间隔的平均眼压均高于对照组。然而，平均眼压仅在3个月时达到统计学显著差异（17.94±6.78 mmHg对13.39±3.09 mmHg，P = 0.003）。SCD患者的平均生存时间显著缩短（10.4±0.7个月对对照组的11.7±0.2个月，对数秩检验=4.1，P = 0.04）。12个月后，SCD患者的累积成功概率为76.5%，对照组为94.7%。
AGV植入术后的SCD可能是手术失败的一个危险因素。需要进行一项更大规模、随访时间更长的前瞻性研究来证实本研究结果。
