Suppr超能文献

腹腔镜手术治疗老年结直肠癌患者的长期疗效:单中心匹配病例对照研究。

Long-term outcomes of laparoscopic surgery in elderly patients with colorectal cancer: A single institutional matched case-control study.

机构信息

Department of Surgery, Hiroshima City Asa Citizens Hospital, Hiroshima, Japan.

Department of Gastroenterological Surgery, Hiroshima Prefectural Hospital, Hiroshima, Japan.

出版信息

Asian J Endosc Surg. 2021 Apr;14(2):200-206. doi: 10.1111/ases.12848. Epub 2020 Aug 16.

Abstract

INTRODUCTION

The number of elderly patients with colorectal cancer has gradually increased. Laparoscopic colorectal surgery is widely used to approach colorectal cancer. The aim of this study was to evaluate long-term outcomes in octogenarians who underwent laparoscopic colorectal surgery for colorectal cancer.

METHODS

This study included 158 patients aged 80 or over who underwent surgery for colorectal cancer between 2010 and 2015. We compared long-term outcomes of a laparoscopic colorectal surgery group with those of an open colorectal surgery group by propensity score matching equalizing factors that could affect prognosis such as prognostic nutritional index and Charlson comorbidity index score.

RESULTS

Forty-eight pairs were selected after propensity score matching. The cancer-specific 5-year survival rate was 97.1% in the laparoscopic colorectal surgery group and 87.6% in the open colorectal surgery group (P = .17). The overall 5-year survival rate was 77.3% in the laparoscopic colorectal surgery group and 73.9% in the open colorectal surgery group (P = .32). The 5-year recurrence-free survival rate was 95.1% in the laparoscopic colorectal surgery group and 85.4% in the open colorectal surgery group (P = .14).

CONCLUSION

Laparoscopic colorectal surgery for octogenarians with colorectal cancer achieves similar oncological outcomes to open colorectal surgery and should be considered as a treatment option.

摘要

介绍

老年结直肠癌患者的数量逐渐增加。腹腔镜结直肠手术广泛应用于结直肠癌的治疗。本研究旨在评估 80 岁以上接受腹腔镜结直肠手术治疗结直肠癌患者的长期疗效。

方法

本研究纳入了 2010 年至 2015 年期间接受结直肠癌手术的 158 例 80 岁以上的患者。我们通过倾向评分匹配,比较了腹腔镜结直肠手术组和开腹结直肠手术组的长期疗效,匹配了可能影响预后的因素,如预后营养指数和 Charlson 合并症指数评分。

结果

倾向评分匹配后选择了 48 对。腹腔镜结直肠手术组的癌症特异性 5 年生存率为 97.1%,开腹结直肠手术组为 87.6%(P =.17)。腹腔镜结直肠手术组的总体 5 年生存率为 77.3%,开腹结直肠手术组为 73.9%(P =.32)。腹腔镜结直肠手术组的 5 年无复发生存率为 95.1%,开腹结直肠手术组为 85.4%(P =.14)。

结论

对于 80 岁以上的结直肠癌患者,腹腔镜结直肠手术与开腹结直肠手术具有相似的肿瘤学疗效,应作为一种治疗选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验