Indigenous Arabs have an intermediate frequency of a Neanderthal-derived COVID-19 risk haplotype compared with other world populations.
作者信息
Mineta Katsuhiko, Goto Kosuke, Gojobori Takashi, Alkuraya Fowzan S
机构信息
Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.
Department of Genetics, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
出版信息
Clin Genet. 2021 Mar;99(3):484-485. doi: 10.1111/cge.13885. Epub 2020 Nov 27.
Abstract
摘要
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The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.严重 COVID-19 的主要遗传风险因素来自尼安德特人。
Nature. 2020 Nov;587(7835):610-612. doi: 10.1038/s41586-020-2818-3. Epub 2020 Sep 30.
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Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.COVID-19 危重症患者的 I 型 IFN 免疫先天缺陷。
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Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations.本土阿拉伯人是最早从古欧亚人群中分化出来的后裔。
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