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维生素 A、B、C 和 D:皮肤科医生的简短综述。

Vitamins A, B, C, and D: A Short Review for the Dermatologist.

出版信息

Altern Ther Health Med. 2021 Jul;27(4):41-49.

Abstract

BACKGROUND

Vitamins and their derivatives are used extensively in the field of dermatology to treat a range of conditions, both benign and malignant. Additionally, over the past decade, vitamin supplements have been heavily advertised for improving overall health. Due to the widespread use of vitamins and their derivatives for dermatologic conditions, a comprehensive review of the evidence is needed.

OBJECTIVE

Here we review several of the well-established uses of vitamins A, B, C, and D in the management of dermatologic conditions ranging from acne vulgaris to malignant melanoma. Additionally, we examine the dermatologic consequences of both deficiency and excess of vitamins A, B, C, and D. Finally, we delve into newer applications for these vitamins and evaluate the evidence behind them.

CONCLUSION

Vitamins, in both topical and oral forms, play a key role in treating many dermatologic conditions. Some of the newer applications of vitamins, such as the use of vitamin B3 for non-melanoma skin cancer prevention, vitamin B6 for prevention of chemotherapy-induced alopecia, and vitamin C as an adjuvant treatment for malignant melanoma, appear promising. Further data is needed to validate these findings. Additionally, many people use vitamin B7 for hair, skin, and nail health. There is evidence that supports vitamin B7 supplementation in patients with uncombable hair syndrome, brittle nail syndrome, and seborrheic dermatitis. Some studies Some studies have also demonstrated a benefit in healthy individuals, although other studies have shown a neutral effect. Further randomized controlled trials are needed. Likewise, the use of vitamin D for the treatment of atopic dermatitis has conflicting results and requires further investigation. New research continues to emerge regarding vitamin supplementation, and it is an important topic for dermatologists.

摘要

背景

维生素及其衍生物在皮肤科领域被广泛用于治疗各种良性和恶性疾病。此外,在过去十年中,维生素补充剂被大量宣传用于改善整体健康。由于维生素及其衍生物广泛用于皮肤科疾病,因此需要对证据进行全面审查。

目的

我们在此回顾了维生素 A、B、C 和 D 在治疗从寻常痤疮到恶性黑色素瘤等皮肤科疾病方面的几种已确立用途。此外,我们还检查了维生素 A、B、C 和 D 缺乏和过量的皮肤科后果。最后,我们深入研究了这些维生素的新应用,并评估了其背后的证据。

结论

维生素(包括局部和口服形式)在治疗许多皮肤科疾病方面发挥着关键作用。一些维生素的新应用,例如使用维生素 B3 预防非黑色素瘤皮肤癌、维生素 B6 预防化疗引起的脱发,以及维生素 C 作为恶性黑色素瘤的辅助治疗,似乎很有前景。需要更多的数据来验证这些发现。此外,许多人使用维生素 B7 来促进头发、皮肤和指甲健康。有证据表明,维生素 B7 补充剂可用于治疗不可梳理综合征、脆性指甲综合征和脂溢性皮炎患者。一些研究表明在健康个体中也有获益,尽管其他研究显示中性效果。需要进一步的随机对照试验。同样,维生素 D 治疗特应性皮炎的结果存在争议,需要进一步研究。关于维生素补充的新研究不断涌现,这是皮肤科医生的一个重要课题。

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