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影响出院后受伤儿童阿片类药物管理的因素。

Factors affecting opioid management for injured children after hospital discharge.

机构信息

Primary Care-Population Medicine Program, Alpert Medical School of Brown University, 222 Richmond St, Providence, RI, USA 02903.

Departments of Emergency Medicine and Pediatrics, Alpert Medical School of Brown University, 222 Richmond St, Providence, RI, USA 02903.

出版信息

J Pediatr Surg. 2021 Mar;56(3):506-511. doi: 10.1016/j.jpedsurg.2020.10.016. Epub 2020 Oct 24.

Abstract

INTRODUCTION

Prescription opioid misuse is a national crisis. Injured children often receive opioid medication at hospital discharge, but the role these prescriptions play in the opioid crisis has not been fully elucidated. Whether these opioids are administered, the duration of severe pain requiring opioids, and what the final disposition of unused opioids is in this population remain unknown.

METHODS

A survey of parent/guardian perceptions of their child's pain after injury, duration of opioid administration, opioid storage and disposal, and perceptions of opioid education was designed. During a 12-month period, parents of injured children admitted to an ACS Level 1 Pediatric Trauma Center were prospectively enrolled by convenience sample. Surveys were in two steps with an enrollment survey prior to discharge and a follow-up survey 7-10 days after discharge.

RESULTS

Seventy of 114 (61.4%) enrolled parents/guardians completed follow-up survey. Of the 79.1% that reported an opioid prescription for their child, 92.5% filled it. Of those reporting on opioid usage, 10.4% never used the opioid, 75% used opioids <3 days, 12.5% 4-7 days, 2% >7 days. Of those who filled the opioid prescription, 83.7% reported having leftover doses. Reasons for discontinuing opioids included the child no longer had pain (87.2%), the child ran out of medication (5.1%), other (7.7%). Regarding storage, 53.3% reported utilizing an unlocked bathroom cabinet, and 81.3% unlocked kitchen space. Of those reporting unused opioids, 83.3% reported not disposing them, and 38.2% reported no plan for disposal.

CONCLUSION

The majority of parents/guardians of injured children report resolution of severe pain requiring opioids within 72 h of hospital discharge, and virtually all by 7 days. The majority of injured children were prescribed a greater number of doses than they needed to treat their pain. Many parents/guardians store opioids in unsecure locations and a significant proportion report no plan to dispose of unused opioid doses. Further investigation is warranted to quantify and address the gap between pain control needs and opioid prescribing practices. The rate of unsecure storage and plan to retain unused opioids are potential targets for discharge opioid education.

TYPE OF STUDY

Cross-sectional survey.

LEVEL OF EVIDENCE

Level IV.

摘要

引言

处方类阿片类药物滥用是一个全国性危机。受伤的儿童在出院时经常会接受阿片类药物治疗,但这些处方在阿片类药物危机中所扮演的角色尚未得到充分阐明。在该人群中,这些阿片类药物是否被使用,需要使用阿片类药物来缓解严重疼痛的持续时间,以及未使用的阿片类药物的最终处置方式仍然未知。

方法

设计了一项调查,以了解父母/监护人对受伤后孩子疼痛的看法、阿片类药物的使用时间、阿片类药物的储存和处置情况,以及对阿片类药物教育的看法。在 12 个月的时间里,通过便利抽样,前瞻性地招募了一家 ACS 一级儿科创伤中心收治的受伤儿童的父母/监护人。调查分为两步进行,在出院前进行登记调查,出院后 7-10 天进行随访调查。

结果

74 名登记的父母/监护人中的 70 名完成了随访调查。在报告为孩子开具阿片类药物处方的 79.1%中,92.5%的人已开具处方。在报告使用阿片类药物的人中,10.4%的人从未使用过阿片类药物,75%的人使用阿片类药物<3 天,12.5%的人使用 4-7 天,2%的人使用>7 天。在开了阿片类药物处方的人中,83.7%的人报告说还有剩余的剂量。停止使用阿片类药物的原因包括孩子不再疼痛(87.2%)、孩子的药物用完了(5.1%)和其他原因(7.7%)。关于储存方式,53.3%的人报告说使用了未上锁的浴室柜子,81.3%的人报告说使用了未上锁的厨房空间。在报告未使用阿片类药物的人中,83.3%的人表示没有处理这些药物,38.2%的人表示没有处理计划。

结论

受伤儿童的大多数父母/监护人报告说,在出院后 72 小时内,严重疼痛需要使用阿片类药物的情况得到缓解,几乎所有儿童在 7 天内都得到缓解。大多数受伤儿童被开具的阿片类药物剂量超过了治疗疼痛所需的剂量。许多父母/监护人将阿片类药物存放在不安全的地方,很大一部分人报告说没有处理未使用的阿片类药物的计划。有必要进一步调查,以量化和解决疼痛控制需求与阿片类药物处方实践之间的差距。不安全储存阿片类药物和保留未使用阿片类药物的计划是出院时阿片类药物教育的潜在目标。

研究类型

横断面调查。

证据水平

四级。

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