Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Jacksonville, Florida.
Clinical Research Internship Study Program (CRISP), Mayo Clinic, Jacksonville, Florida.
Transplant Proc. 2021 Jan-Feb;53(1):30-35. doi: 10.1016/j.transproceed.2020.10.026. Epub 2020 Nov 25.
At our institution, peripherally inserted, 8.5-French rapid-infusion catheters (RICs) are placed for high-flow administration of intravenous fluids and blood products during liver transplant (LT). We sought to estimate the incidence of RIC placement-associated complications in LT patients.
Electronic health records of all patients who underwent LT from January 2008 through December 2017 were retrospectively reviewed. RIC-related complications were deemed clinically significant if they required surgical consultation or intervention due to infiltration. Univariable and multivariable logistic regression analyses were used to evaluate associations between patient characteristics and RIC complications.
In total, 839 LT patients who received RICs were identified; of these, 14 (1.67%) had RIC-related complications, and 7 (0.83%) required surgical consultation. No patients needed fasciotomy or wound débridement due to a RIC complication, and no patients had permanent sequelae. In the multivariable logistic regression analysis, only an increase in international normalized ratio (INR) from 1.4 to 2.2 (equivalent to the interquartile range of observed INR values) increased the odds of complications due to RIC placement (odds ratio [95% CI], 1.98 [1.10-3.56]; P = .02).
We observed a low incidence of perioperative RIC-related complications (1.7%). No patients had permanent RIC-related complications.
在我们机构，经外周插入的 8.5 French 快速输注导管（RIC）用于肝移植（LT）期间静脉输注液体和血液制品的高流量输注。我们旨在评估 LT 患者中 RIC 置管相关并发症的发生率。
回顾性分析 2008 年 1 月至 2017 年 12 月期间所有接受 LT 的患者的电子病历。如果由于浸润而需要外科会诊或干预，则认为 RIC 相关并发症具有临床意义。使用单变量和多变量逻辑回归分析评估患者特征与 RIC 并发症之间的关联。
共确定了 839 例接受 RIC 的 LT 患者；其中，14 例（1.67%）出现 RIC 相关并发症，7 例（0.83%）需要外科会诊。没有患者因 RIC 并发症需要筋膜切开术或伤口清创术，也没有患者出现永久性后遗症。在多变量逻辑回归分析中，只有 INR 从 1.4 增加到 2.2（相当于观察到的 INR 值的四分位距）增加了因 RIC 置管而发生并发症的几率（比值比[95%CI]，1.98[1.10-3.56]；P=0.02）。
我们观察到围手术期 RIC 相关并发症的发生率较低（1.7%）。没有患者出现永久性 RIC 相关并发症。
