Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Leeds, UK.
Academic Department of Trauma and Orthopaedics, Leeds General Infirmary, University of Leeds, Leeds, UK.
Knee Surg Sports Traumatol Arthrosc. 2022 Feb;30(2):638-651. doi: 10.1007/s00167-020-06358-x. Epub 2020 Nov 27.
The purpose of this study was to perform a systematic review and meta-analysis to compare clinical and patient-reported outcome measures of medially stabilised (MS) TKA when compared to other TKA designs.
The Preferred Reporting Items for Systematic Review and Meta-Analyses algorithm was used. The Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE, and EMCARE databases were searched to June 2020. Studies with a minimum of 12 months of follow-up comparing an MS TKA design to any other TKA design were included. The statistical analysis was completed using Review Manager (RevMan), Version 5.3.
The 22 studies meeting the inclusion criteria included 3011 patients and 4102 TKAs. Overall Oxford Knee Scores were significantly better (p = 0.0007) for MS TKA, but there was no difference in the Forgotten Joint Scores (FJS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Knee Society Score (KSS)-Knee, KSS-Function, and range of motion between MS and non-MS TKA designs. Significant differences were noted for sub-group analyses; MS TKA showed significantly worse KSS-Knee (p = 0.02) and WOMAC (p = 0.03) scores when compared to Rotating Platform (RP) TKA while significantly better FJS (p = 0.002) and KSS-knee scores (p = 0.0001) when compared to cruciate-retaining (CR) TKA.
This review and meta-analysis show that MS TKA designs result in both patient and clinical outcomes that are comparable to non-MS implants. These results suggest implant design alone may not provide further improvement in patient outcome following TKA, surgeons must consider other factors, such as alignment to achieve superior outcomes.
III.
本研究旨在进行系统评价和荟萃分析,比较内侧稳定(MS)TKA 与其他 TKA 设计的临床和患者报告结局测量。
采用系统评价和荟萃分析首选报告项目(PRISMA)算法。检索了 Cochrane 中央对照试验注册库、MEDLINE、EMBASE 和 EMCARE 数据库,检索时间截至 2020 年 6 月。纳入了比较 MS TKA 设计与任何其他 TKA 设计的至少 12 个月随访的研究。使用 Review Manager(RevMan),版本 5.3 进行统计分析。
符合纳入标准的 22 项研究共纳入 3011 名患者和 4102 例 TKA。MS TKA 的总体牛津膝关节评分明显更好(p=0.0007),但 MS 和非 MS TKA 设计之间的遗忘关节评分(FJS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、膝关节协会评分(KSS)-膝关节、KSS-功能和活动范围无差异。亚组分析显示存在显著差异;与旋转平台(RP)TKA 相比,MS TKA 的 KSS-膝关节(p=0.02)和 WOMAC(p=0.03)评分明显更差,而与保留交叉韧带(CR)TKA 相比,FJS(p=0.002)和 KSS-膝关节评分(p=0.0001)明显更好。
本综述和荟萃分析表明,MS TKA 设计可获得与非 MS 植入物相当的患者和临床结局。这些结果表明,单独的植入物设计可能不会在 TKA 后进一步改善患者的结局,外科医生必须考虑其他因素,如对线,以获得更好的结果。
III。