Division of Medical Physiology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.
Division of Family Medicine and Primary Care, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; Ceres Hospital, Cape Winelands Health District, Department of Health, Ceres, South Africa.
Reprod Toxicol. 2021 Jan;99:65-70. doi: 10.1016/j.reprotox.2020.11.012. Epub 2020 Nov 26.
Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), a single-stranded RNA virus, was found to be the causal agent of the disease called coronavirus disease. During December 2019, China informed the World Health Organization (WHO) of an outbreak of cases of pneumonia of unknown etiology, which caused severe-acute respiratory distress. The disease was termed coronavirus disease 2019 (Covid-19). Due to alarming levels of spread and severity, on the 11th of March 2020, the WHO declared the outbreak as a global pandemic. As of September 14, 2020, more than 29 million cases have been reported, with over 900,000 deaths globally. Since the outbreak, although not conclusive, discoveries have been made regarding the understanding of the epidemiology, etiology, clinical features, clinical treatment, and prevention of the disease. SARS-COV-2 has been detected in saliva, respiratory fluids, blood, urine, and faeces. Findings are however controversial regarding its presence in the semen or the testis. Hence, this review aimed to further analyse the literature concerning (i) the effects of previously identified human coronaviruses on male fertility (ii) the impact of Covid-19 on male fertility and (iii) the implication for general health in terms of infection and transmission.
严重急性呼吸综合征冠状病毒 2（SARS-COV-2）是一种单链 RNA 病毒，被认为是导致冠状病毒病的病原体。2019 年 12 月，中国向世界卫生组织（WHO）报告了一起不明病因肺炎病例的爆发，导致严重急性呼吸窘迫。该疾病被称为 2019 年冠状病毒病（Covid-19）。由于传播范围和严重程度令人震惊，2020 年 3 月 11 日，世界卫生组织宣布该疫情为全球大流行。截至 2020 年 9 月 14 日，已报告超过 2900 万例病例，全球有超过 90 万人死亡。自疫情爆发以来，尽管尚未得出明确结论，但在了解该疾病的流行病学、病因、临床特征、临床治疗和预防方面取得了一些发现。SARS-COV-2 已在唾液、呼吸道分泌物、血液、尿液和粪便中被检测到。然而，关于其在精液或睾丸中存在的发现存在争议。因此，本综述旨在进一步分析有关以下方面的文献：（i）先前鉴定的人类冠状病毒对男性生育力的影响；（ii）Covid-19 对男性生育力的影响；（iii）感染和传播方面对一般健康的影响。
