Shehata Islam Mohammad, Odell Tiffany D, Elhassan Amir, Urits Ivan, Viswanath Omar, Kaye Alan D
Department of Anesthesiology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Department of Neurosurgery, Desert Regional Medical Center, Palm Springs, CA, USA.
Oncol Ther. 2021 Jun;9(1):13-19. doi: 10.1007/s40487-020-00134-0. Epub 2020 Nov 28.
The introduction of new anticancer treatment modalities has improved survival rates, transforming cancer into a chronic disease in many instances. One of the most devastating complications of cancer treatment is cancer therapy-related cardiac dysfunction. Adequate preoperative assessment of any significant cancer therapy-related cardiac impairment is critical, and may be missed with conventional measures. The assessment of global longitudinal strain by speckle-tracking echocardiography is more sensitive for the early detection of cardiac contractility before a decline in ejection fraction can be discovered. Global longitudinal strain can also predict postoperative cardiac dysfunction, which makes it a good alternative for preoperative cardiac assessment in the oncology population when cancer therapies have been administered that can alter normal performance.
新的抗癌治疗方式的引入提高了生存率，在许多情况下将癌症转变为一种慢性疾病。癌症治疗最具破坏性的并发症之一是癌症治疗相关的心脏功能障碍。对任何严重的癌症治疗相关心脏损害进行充分的术前评估至关重要，而传统方法可能会遗漏这种评估。通过斑点追踪超声心动图评估整体纵向应变在射血分数下降之前对心脏收缩力的早期检测更为敏感。整体纵向应变还可以预测术后心脏功能障碍，这使其成为接受过可能改变正常心脏功能的癌症治疗的肿瘤患者术前心脏评估的良好选择。
