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一名患有边缘性脑炎、耳软骨膜炎和巩膜外层炎的患者——复发性多软骨炎的罕见表现

A Patient with Limbic Encephalitis, Ear Perichondritis, and Episcleritis - An Unusual Presentation of Relapsing Polychondritis.

作者信息

Angkodjojo Stanley, Yeo Crystal Jing Jing

机构信息

Department of General Medicine (Rheumatology), Sengkang General Hospital, Singapore, Singapore.

Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore.

出版信息

Case Rep Neurol. 2020 Nov 3;12(3):378-386. doi: 10.1159/000510634. eCollection 2020 Sep-Dec.

Abstract

Relapsing polychondritis (RPC) is a rare autoimmune disease that is characterized by recurrent inflammation and destruction of cartilaginous tissues. Limbic encephalitis is a rare central nervous system manifestation of RPC that has been mentioned in case reports. Recognition of this association, and reliable methods of diagnosis, including the utility of neuroimaging modalities such as positron emission tomography/computed tomography (PET/CT) can be useful in the evaluation of this diagnostic challenge. We report a patient with limbic encephalitis associated with RPC, where PET/CT was effectively used in the diagnosis, and monitoring of response to treatment. We also demonstrate that it can be a useful modality in certain situations when brain magnetic resonance imaging cannot be done.

摘要

复发性多软骨炎(RPC)是一种罕见的自身免疫性疾病,其特征是软骨组织反复发生炎症和破坏。边缘性脑炎是RPC一种罕见的中枢神经系统表现,已有病例报告提及。认识到这种关联以及可靠的诊断方法,包括正电子发射断层扫描/计算机断层扫描(PET/CT)等神经影像学检查方法的应用,有助于应对这一诊断难题。我们报告了1例与RPC相关的边缘性脑炎患者,PET/CT在该患者的诊断及治疗反应监测中发挥了有效作用。我们还证明,在无法进行脑磁共振成像的某些情况下,PET/CT可能是一种有用的检查方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dda8/7670367/3a371985c4e5/crn-0012-0378-g01.jpg

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