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Loss of Phosphatase and Tensin Homolog Promotes Cardiomyocyte Proliferation and Cardiac Repair After Myocardial Infarction.

作者信息

Liang Tian, Gao Feng, Jiang Jun, Lu Yao Wei, Zhang Feng, Wang Yingchao, Liu Ning, Fu Xuyang, Dong Xiaoxuan, Pei Jianqiu, Cowan Douglas B, Hu Xinyang, Wang Jian'an, Wang Da-Zhi, Chen Jinghai

机构信息

Department of Cardiology, Provincial Key Lab of Cardiovascular Research, Second Affiliated Hospital (T.L., F.G., J.J., F.Z., N.L., X.F., X.D., X.H., J.W., J.C.), Hangzhou, China.

Institute of Translational Medicine (T.L., F.G., F.Z., N.L., X.F., X.D., J.C.), Hangzhou, China.

出版信息

Circulation. 2020 Dec;142(22):2196-2199. doi: 10.1161/CIRCULATIONAHA.120.046372. Epub 2020 Nov 30.

Abstract
摘要

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本文引用的文献

1
Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction.
Nat Commun. 2019 Apr 17;10(1):1802. doi: 10.1038/s41467-019-09530-1.
2
mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts.
Circ Res. 2013 Jun 7;112(12):1557-66. doi: 10.1161/CIRCRESAHA.112.300658. Epub 2013 Apr 10.
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Inducible and cardiac specific PTEN inactivation protects ischemia/reperfusion injury.
J Mol Cell Cardiol. 2009 Feb;46(2):193-200. doi: 10.1016/j.yjmcc.2008.10.021. Epub 2008 Nov 7.
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Loss of PTEN attenuates the development of pathological hypertrophy and heart failure in response to biomechanical stress.
Cardiovasc Res. 2008 Jun 1;78(3):505-14. doi: 10.1093/cvr/cvn041. Epub 2008 Feb 15.

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