Hong R
Department of Pediatrics, University of Wisconsin, Madison 53792.
Immunol Invest. 1987 Oct;16(6):453-99. doi: 10.3109/08820138709087098.
Immunodeficiency disease is rapidly increasing in frequency. The AIDS epidemic, the increasing use of transplantation with immunosuppression, the aggressive immunotherapy, the persistent deficiencies after bone marrow transplantation--all contribute to the astronomically increasing numbers of patients with host defense failure. This review has presented my viewpoint as to the approaches which can be utilized by practitioners with varying focal points to provide diagnosis and maximize the potential for a cure today or at least to provide the beginnings of understanding from which will come the cures of tomorrow.
免疫缺陷疾病的发病率正在迅速上升。艾滋病的流行、免疫抑制下移植手术使用的增加、激进的免疫疗法、骨髓移植后持续存在的缺陷——所有这些都导致宿主防御功能衰竭的患者数量呈天文数字增长。这篇综述阐述了我的观点,即不同侧重点的从业者可以采用哪些方法来进行诊断,并最大程度地提高当前治愈的可能性,或者至少为未来的治愈奠定理解基础。