Zhang G H, Wang M, Chen G, Yu J A, Ma H, Ou X J, Wang Y
Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Department of Interventional Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Zhonghua Gan Zang Bing Za Zhi. 2020 Nov 20;28(11):949-953. doi: 10.3760/cma.j.cn501113-20190909-00328.
To evaluate the effectiveness and safety of transjugular liver biopsy (TJLB) in clinical applications. Clinical data of patients who underwent TJLB in the Beijing Friendship Hospital Affiliated to Capital Medical University from November 2017 to March 2019 were retrospectively reviewed. Clinical characteristics, indications and biopsy complications and the samples quality were analyzed. Among 61 cases who underwent TJLB, 32 were males and 29 were females, aged 16 to 79 years. There were 43 cases (70.5%) with abnormal coagulation function, among which the prothrombin time activity percentage (39%) and platelet count (24×10(9)/L ) were lowest. 38 cases (62.3%) had perihepatic fluid. One case was obese, and had a body mass index of 31kg/m2. 56 cases (91.8%) were successfully biopsied. 51 cases (83.6%) liver tissue samples were assessed with pathological diagnosis. Five cases (8.2%) had serious complications. 14 cases (23.0%) had mild complications, and no patients died. TJLB is a safe and feasible method for patients who have contraindications to percutaneous liver biopsy.
评估经颈静脉肝活检（TJLB）在临床应用中的有效性和安全性。回顾性分析2017年11月至2019年3月在首都医科大学附属北京友谊医院接受TJLB的患者的临床资料。分析临床特征、适应证、活检并发症及样本质量。在61例行TJLB的患者中，男性32例，女性29例，年龄16至79岁。43例（70.5%）凝血功能异常，其中凝血酶原时间活动度百分比最低为39%，血小板计数最低为24×10⁹/L。38例（62.3%）有肝周积液。1例肥胖患者，体重指数为31kg/m²。56例（91.8%）成功进行活检。51例（83.6%）肝组织样本经病理诊断评估。5例（8.2%）发生严重并发症。14例（23.0%）发生轻度并发症，无患者死亡。TJLB对于经皮肝活检有禁忌证的患者是一种安全可行的方法。
