Department of Physiology and Biochemistry, Faculty of Veterinary Medicine, University of Belgrade, Belgrade, Serbia.
Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
J Dairy Res. 2020 Nov;87(4):429-435. doi: 10.1017/S0022029920001077. Epub 2020 Dec 2.
This research paper addresses the hypothesis that an oral supplementation with organically modified clinoptilolite will improve colostrum quality in primiparous dairy cows whilst having no adverse effects on the cows' health. A total of 36 pregnant Holstein primiparous dairy cattle were randomly assigned to receive daily oral drenching, two hours following morning feeding, with 1 l of water containing either 0 g/l (n = 16) or 150 g/l (n = 20) of clinoptilolite. Treatment lasted from 24 ± 4 d prior to expected parturition until two days postpartum (pp). Colostrum was collected at 2 to 3 h, 12, 24 and 36 h pp and blood samples were collected at 24 ± 4 and 4 ± 2 d prior to parturition and 1, 2 and 7 d pp. Overall mean dry matter, fat and total protein percentage as well as IgG concentration and mass were significantly greater in colostrum collected from cattle drenched with clinoptilolite (total protein increased by 15% and IgG concentration and mass by 21 and 38% respectively at first sampling and further at second sampling). Total γ globulin and most other blood serum biochemistry parameters did not differ between cattle treated and not treated with clinoptilolite, the only exception being the fast anionic γ globulin fraction that was 17% greater at 4 ± 2 d prior to parturition and 10% lower on the 1st day pp in treated cattle. These results showed that organically modified oral clinoptilolite supplementation at 150 g/d significantly increases the IgG concentration in colostrum and has no adverse effects on the energy status, protein, lipid, and mineral metabolism in primiparous dairy cattle during prepartum period.
本研究论文探讨了一个假设，即有机改性斜发沸石的口服补充剂将改善初产奶牛的初乳质量，同时对奶牛的健康没有不良影响。总共 36 头怀孕的荷斯坦初产奶牛被随机分配，在早上喂食后两小时内每天口服 1 升含有 0 g/l（n = 16）或 150 g/l（n = 20）斜发沸石的水。治疗从预期分娩前 24 ± 4 天持续到产后两天（pp）。在产后 2 至 3 小时、12、24 和 36 小时采集初乳，并在分娩前 24 ± 4 天和 4 ± 2 天以及产后 1、2 和 7 天采集血液样本。用斜发沸石处理的奶牛采集的初乳的总干物质、脂肪和总蛋白百分比以及 IgG 浓度和质量总体上显著更高（总蛋白在第一次采样时增加了 15%，IgG 浓度和质量分别增加了 21%和 38%，第二次采样时进一步增加）。用斜发沸石处理和未处理的奶牛之间的总 γ 球蛋白和大多数其他血清生化参数没有差异，唯一的例外是快速阴离子 γ 球蛋白部分，在分娩前 4 ± 2 天增加了 17%，在产后第 1 天降低了 10%。这些结果表明，每天 150 g 口服有机改性斜发沸石补充剂显著增加了初乳中的 IgG 浓度，并且对产前期间初产奶牛的能量状态、蛋白质、脂质和矿物质代谢没有不良影响。
