Department of Family and Community Medicine, University of North Dakota School of Medicine, Grand Forks, ND, USA.
Department of Internal Medicine, University of North Dakota School of Medicine, Grand Forks, ND, USA.
J Dermatolog Treat. 2022 May;33(3):1576-1580. doi: 10.1080/09546634.2020.1859442. Epub 2021 Jan 28.
The aim of this study was to examine the trends and risk factors of antibiotic treatment for skin and soft tissue infections (SSTIs), in the United States.
We conducted a retrospective analysis of SSTIs visits utilizing the 2011-2016 National Ambulatory Medical Care Survey.
There were over 43 million visits for SSTIs in the US. We found no association between antibiotic treatment and gender, age, race, insurance, region, and metropolitan statistical area. Methicillin-resistant (MRSA) antibiotics were prescribed at 34.8% of SSTI visits, methicillin-sensitive (MSSA) antibiotics at 27.5%, and other antibiotics at 21.7%. Among visits treated with an antibiotic, 40.4% ( = 378) received an antibiotic with MSSA coverage, while 59.6% ( = 558) received an antibiotic with MRSA coverage. Region where the visit occurred was associated with the use of MSSA versus MRSA antibiotics ( = .013). Mean age of visits receiving MSSA antibiotics was significantly older than visits receiving MRSA antibiotics, 53.8 ± 1.2 vs. 50.9 ± 0.9 ( = .045).
This study found that providers more frequently utilize antibiotics with MRSA coverage for SSTIs. Antibiotic class chosen was associated with region, with MRSA coverage antibiotics more likely to be prescribed in the South. Additionally, individuals receiving antibiotics with MSSA coverage were older than those receiving antibiotics with MRSA coverage.
本研究旨在探讨美国皮肤和软组织感染（SSTIs）抗生素治疗的趋势和危险因素。
我们利用 2011-2016 年全国门诊医疗调查对 SSTIs 就诊进行了回顾性分析。
美国有超过 4300 万例 SSTIs 就诊。我们发现抗生素治疗与性别、年龄、种族、保险、地区和都市区没有关联。34.8%的 SSTI 就诊开具了耐甲氧西林金黄色葡萄球菌（MRSA）抗生素，27.5%开具了甲氧西林敏感金黄色葡萄球菌（MSSA）抗生素，21.7%开具了其他抗生素。在接受抗生素治疗的就诊中，40.4%（ = 378）接受了具有 MSSA 覆盖范围的抗生素，59.6%（ = 558）接受了具有 MRSA 覆盖范围的抗生素。就诊发生的地区与 MSSA 与 MRSA 抗生素的使用相关（ = .013）。接受 MSSA 抗生素治疗的就诊的平均年龄明显大于接受 MRSA 抗生素治疗的就诊，分别为 53.8 ± 1.2 岁和 50.9 ± 0.9 岁（ = .045）。
本研究发现，提供者更频繁地使用具有 MRSA 覆盖范围的抗生素治疗 SSTIs。抗生素类别与地区相关，MRSA 覆盖范围的抗生素更可能在南部地区开具。此外，接受 MSSA 覆盖范围抗生素治疗的个体比接受 MRSA 覆盖范围抗生素治疗的个体年龄更大。
