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撤回:癌症相关成纤维细胞来源的细胞外囊泡诱导的微小RNA-30e缺失通过与CTHRC1结合促进乳腺癌进展。

RETRACTED: Loss of microRNA-30e induced by extracellular vesicles from cancer-associated fibroblasts promotes breast cancer progression by binding to CTHRC1.

作者信息

Xi Chunfang, Wang Jiangfen, Sun Haichen, Zhang Xuran, Kang Hua

机构信息

Department of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, PR China; Department of Breast Surgery, Shanxi Provincial People's Hospital, Taiyuan 030012, Shanxi, PR China.

Department of Breast Surgery, Shanxi Provincial People's Hospital, Taiyuan 030012, Shanxi, PR China.

出版信息

Exp Mol Pathol. 2021 Feb;118:104586. doi: 10.1016/j.yexmp.2020.104586. Epub 2020 Nov 29.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors as “some data in this study are not solid enough and need to be further explored”. The authors stated that they "found abnormalities in the re-identification of CAF-EVs, the extracted extracellular vesicles may be polluted and the elliptical structure under electron microscope is not owned by CAF-EVs. The identification of CAF-EVs by Western Blots did not refer to the definition of international society." The authors informed the journal that, after the re-experiment, they found that "there is no vesicle specific protein expression, whether the results of subsequent experiments are generated by CAF-EVs needs to be re-tested".

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