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世卫组织欧洲国家(2018-2019 年)人乳头瘤病毒疫苗接种建议、资金和覆盖情况的现状。

The status of human papillomavirus vaccination recommendation, funding, and coverage in WHO Europe countries (2018-2019).

机构信息

Department of Health Sciences, University of Florence , Florence, Italy.

Market Access Vaccines, MSD , Lyon, France.

出版信息

Expert Rev Vaccines. 2020 Nov;19(11):1073-1083. doi: 10.1080/14760584.2020.1858057. Epub 2020 Dec 14.

Abstract

: There is a need to better understand HPV vaccination (HPVv) implementation in WHO Europe Region (WHO/ER), including recommendations, funding, and vaccination coverage rates (VCR). : A targeted literature review (up to 31 January 2020) was conducted using national health ministry websites, WHO database, and published studies from WHO/ER countries (n = 53). HPVv recommendations and funding data (target age, gender, schedule, setting, target and monitored VCR) for primary and catch-up cohorts were collected. : National recommendations for HPVv exist in 46/53 (87%) countries, of which 38 (83%), 2 (4%), and 6 (13%) countries provided full, partial, or no funding, respectively, for the primary cohort. Fully or partially funded HPVv was provided for girls only in 25/53 (47%) countries and for both boys and girls in 15/53 (28%) countries. HPVv catch-up was fully or partially funded in 14/53 (26%) countries. Among 40 countries with a national immunization program (NIP), monitored VCRs ranged from 4.3% to 99% (n = 30). Of the 10 countries reporting VCR targets, only Portugal exceeded its target. : Of the 53 WHO/ER countries, 40 have funded HPVv NIPs, among which 30 report VCRs. Additional efforts are required to ensure HPVv NIPs are fully funded and high VCRs maintained.

摘要

: 需要更好地了解世卫组织欧洲区域(世卫组织/欧洲区域)的 HPV 疫苗接种(HPVv)实施情况,包括建议、资金和疫苗接种覆盖率(VCR)。 : 对国家卫生部网站、世卫组织数据库和世卫组织/欧洲区域国家发表的研究进行了针对性文献综述(截至 2020 年 1 月 31 日)(n=53)。收集了初级和补种队列的 HPVv 建议和资金数据(目标年龄、性别、时间表、接种地点、目标和监测 VCR)。 : 在 53 个国家中,有 46 个(87%)国家有 HPVv 建议,其中 38 个(83%)、2 个(4%)和 6 个(13%)国家分别为初级队列提供全额、部分或无资金。25 个(47%)国家仅为女孩提供全额或部分资金的 HPVv,15 个(28%)国家为男孩和女孩提供全额或部分资金的 HPVv。14 个(26%)国家全额或部分资助 HPVv 补种。在有国家免疫规划(NIP)的 40 个国家中,监测的 VCR 范围从 4.3%到 99%(n=30)。在报告 VCR 目标的 10 个国家中,只有葡萄牙超过了目标。 : 在 53 个世卫组织/欧洲区域国家中,有 40 个国家资助了 HPVv NIP,其中 30 个国家报告了 VCR。需要进一步努力,确保 HPVv NIP 得到充分资助并保持高 VCR。

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