Department of Orthopaedics, Catholic University of Rome-Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Institute of Biochemistry and Clinical Biochemistry, Catholic University of Rome-Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Hip Int. 2020 Dec;30(2_suppl):52-58. doi: 10.1177/1120700020971661.
The aim of this study is to evaluate clinical, radiographic and laboratory results of ceramic-on-metal (CoM) (hybrid hard bearing) in total hip arthroplasty (THA), associated with a short stem implant.
From a cohort of 37 patients suffering from primary or secondary hip osteoarthritis who underwent THA using CoM bearing, 19 were suitable for this study. All procedures were performed by the same surgeon using a posterior-lateral approach. All patients were compared clinically using the Harris Hip Score (HHS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analogue scale (VAS), 12-item Short Form Health Survey (SF12F/M), and radiographically (offset, CD angle, limb length discrepancy, cup inclination and anteversion, subsidence, osseointegration, heterotopic ossification). Blood samples were collected in order to evaluate chromium (Cr) and cobalt (Co) ions level. Radiographic evaluations were carried out by 3 different blinded surgeons. A statistical analysis was performed.
At a mean follow-up of 97 (73-125) months all implanted stems were well-positioned and osseointegrated. Clear improvements were observed for clinical scores comparing preoperative and postoperative values. Radiographic evaluation showed a good ability to restore proper articular geometry. Cr ion analysis revealed values below the safety threshold except for 1 case. Serum levels of Co were below the threshold in all patients. There was a statistically significant correlation only between Cr metal ions and length of follow-up.
CoM bearing has proven to be reliable and safe at a mean 8-year follow-up for patients in whom the components were correctly implanted. The rise of blood metal ions was minimal and involved neither systemic or local toxicity nor influenced clinical results.
本研究旨在评估陶瓷对金属(CoM)(混合硬轴承)在全髋关节置换(THA)中的临床、影像学和实验室结果,该研究与短柄植入物相关。
从接受 CoM 轴承 THA 的 37 例原发性或继发性髋骨关节炎患者的队列中,有 19 例符合本研究条件。所有手术均由同一位外科医生通过后外侧入路进行。所有患者均采用 Harris 髋关节评分(HHS)、安大略西部和麦克马斯特大学骨关节炎指数(WOMAC)、视觉模拟评分(VAS)、12 项简明健康调查(SF12F/M)进行临床比较,并进行影像学检查(偏心距、CD 角、肢体长度差异、杯倾斜和前倾角、下沉、骨整合、异位骨化)。收集血样以评估铬(Cr)和钴(Co)离子水平。由 3 名不同的盲法外科医生进行影像学评估。进行了统计学分析。
在平均 97(73-125)个月的随访中,所有植入的柄均位置良好且骨整合良好。与术前相比,临床评分均有明显改善。影像学评估显示,关节几何形状的恢复能力良好。Cr 离子分析显示,除 1 例外,所有值均低于安全阈值。所有患者的血清 Co 水平均低于阈值。仅 Cr 金属离子与随访时间之间存在统计学显著相关性。
在平均 8 年的随访中,CoM 轴承被证明在正确植入的患者中是可靠和安全的。血液金属离子的升高很小,既没有涉及全身或局部毒性,也没有影响临床结果。