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在 COVID-19 大流行初期,开展全国性前瞻性研究以避免发生扁桃体炎和扁桃体周围脓肿 **解析**:原文为一个医学研究的标题,关键词为“tonsillitis”(扁桃体炎)、“peritonsillar abscess”(扁桃体周围脓肿)、“COVID-19 pandemic”(新冠疫情大流行),译文结合语境,选择了“避免”这个动词,以突显研究的主旨。

Admission avoidance in tonsillitis and peritonsillar abscess: A prospective national audit during the initial peak of the COVID-19 pandemic.

机构信息

Addenbrooke's Hospital, Cambridge, UK.

出版信息

Clin Otolaryngol. 2021 Mar;46(2):363-372. doi: 10.1111/coa.13680. Epub 2020 Dec 17.

Abstract

OBJECTIVES

To report changes in practice brought about by COVID-19 and the implementation of new guidelines for the management of tonsillitis and peritonsillar abscess (PTA), and to explore factors relating to unscheduled re-presentations for patients discharged from the emergency department (ED).

DESIGN

Prospective multicentre national audit over 12 weeks from 6 April 2020.

SETTING

UK secondary care ENT departments.

PARTICIPANTS

Adult patients with acute tonsillitis or PTA.

MAIN OUTCOME MEASURES

Re-presentation within 10 days for patients discharged from the ED.

RESULTS

83 centres submitted 765 tonsillitis and 416 PTA cases. 54.4% (n = 410) of tonsillitis and 45.3% (187/413) of PTAs were discharged from ED. 9.6% (39/408) of tonsillitis and 10.3% (19/184) of PTA discharges re-presented within 10 days, compared to 9.7% (33/341) and 10.6% (24/224) for those admitted from ED. The subsequent admission rate of those initially discharged from ED was 4.7% for tonsillitis and 3.3% for PTAs. IV steroids and antibiotics increased the percentage of patients able to swallow from 35.8% to 72.5% for tonsillitis (n = 270/754 and 441/608) and from 22.3% to 71.0% for PTA (n = 92/413 and 265/373). 77.2% of PTAs underwent drainage (n = 319/413), with no significant difference in re-presentations in those drained vs not-drained (10.6% vs 9.5%, n = 15/142 vs 4/42, P = .846). Univariable logistic regression showed no significant predictors of re-presentation within 10 days.

CONCLUSIONS

Management of tonsillitis and PTA changed during the initial peak of the pandemic, shifting towards outpatient care. Some patients who may previously have been admitted to hospital may be safely discharged from the ED.

摘要

目的

报告 COVID-19 带来的实践变化以及实施扁桃体炎和扁桃体周脓肿(PTA)管理新指南的情况,并探讨与急诊科出院患者非计划再就诊相关的因素。

设计

2020 年 4 月 6 日至 12 周的前瞻性多中心全国性审计。

地点

英国二级保健耳鼻喉科部门。

参与者

患有急性扁桃体炎或 PTA 的成年患者。

主要观察指标

急诊科出院患者 10 天内再次就诊。

结果

83 个中心提交了 765 例扁桃体炎和 416 例 PTA 病例。54.4%(n=410)的扁桃体炎和 45.3%(187/413)的 PTA 从 ED 出院。10 天内,9.6%(39/408)的扁桃体炎和 10.3%(19/184)的 PTA 出院患者再次就诊,而从 ED 入院的患者分别为 9.7%(33/341)和 10.6%(24/224)。最初从 ED 出院的患者随后入院率为扁桃体炎 4.7%,PTA 3.3%。IV 类固醇和抗生素使能够吞咽的患者比例从扁桃体炎的 35.8%增加到 72.5%(n=270/754 和 441/608)和 PTA 的 22.3%增加到 71.0%(n=92/413 和 265/373)。77.2%的 PTA 接受了引流(n=319/413),引流与未引流的患者再次就诊无显著差异(10.6%vs9.5%,n=15/142vs4/42,P=0.846)。单变量逻辑回归显示,10 天内再次就诊无显著预测因素。

结论

大流行初期,扁桃体炎和 PTA 的治疗发生了变化,向门诊治疗转移。一些以前可能住院的患者可以从 ED 安全出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5692/7753410/4fb4efd4ecd6/COA-46-363-g001.jpg

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