From the Department of Dermatology, University of California, San Diego.
Dermatitis. 2021;32(6):430-436. doi: 10.1097/DER.0000000000000702.
Mastisol Liquid Adhesive is widely used on the skin, especially after surgical procedures. It contains gum mastic, gum storax, methyl salicylate, and ethanol.
The aims of the study were to review our experience patch testing patients allergic to Mastisol and to assess coreacting substances.
We identified 18 patients who were allergic to Mastisol. Most of these had a history of postoperative or cardiac electrode dermatitis and underwent patch testing with multiple surgically related substances, including ingredients of Mastisol, compound tincture of benzoin, and fragrance-related ingredients and botanicals.
Among Mastisol-allergic patients, 13 (72%) of 18 were allergic to gum mastic, whereas 7 (44%) of 16 were allergic to gum storax. There was frequent coreactivity with various fragrance-related materials, including Majantol, Styrax benzoin, Myroxylon balsamum, Myroxylon pereirae, propolis, and others. Two gum mastic-allergic patients had positive patch tests with hydroperoxides of linalool and several other linalool-containing essential oils. As gum mastic contains linalool, it may explain some gum mastic reactions. Among patients without a history of postoperative contact dermatitis, 1 (0.4%) of 250 was patch test positive for gum mastic. This patient had allergic contact dermatitis from fragrances, so the gum mastic reaction was likely a true-positive relevant reaction.
Mastisol 液体胶广泛应用于皮肤，尤其是在外科手术后。它含有乳香树胶、苏合香脂、水杨酸甲酯和乙醇。
本研究旨在回顾我们对 Mastisol 过敏患者的斑贴试验经验，并评估共同反应物质。
我们确定了 18 名对 Mastisol 过敏的患者。这些患者大多有术后或心脏电极性皮炎病史，并接受了多种与手术相关物质的斑贴试验，包括 Mastisol 的成分、安息香酊、与香料相关的成分和植物。
在 Mastisol 过敏患者中，18 名患者中有 13 名（72%）对乳香树胶过敏，16 名患者中有 7 名（44%）对苏合香脂过敏。与各种香料相关的材料存在频繁的共同反应，包括 Majantol、安息香、秘鲁香脂、巴西香脂、蜂胶等。2 名乳香树胶过敏患者对芳樟醇的过氧化物和其他几种含芳樟醇的精油呈斑贴试验阳性。由于乳香树胶含有芳樟醇，因此它可能解释了一些乳香树胶反应。在没有术后接触性皮炎病史的患者中，250 名患者中有 1 名（0.4%）对乳香树胶呈斑贴试验阳性。该患者对香料过敏，因此乳香树胶反应可能是真正的阳性相关反应。
