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经睫状体平坦部玻璃体切割术后眼压持续升高的患眼行 Ahmed 青光眼阀植入的长期疗效。

Long-term Outcome of Ahmed Glaucoma Valve Implantation in Eyes With Intractably Raised Intraocular Pressure Following Pars Plana Vitrectomy.

机构信息

Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India.

出版信息

J Glaucoma. 2021 Apr 1;30(4):362-367. doi: 10.1097/IJG.0000000000001749.

Abstract

PRECIS

Ahmed glaucoma valve (AGV) implantation led to a significant reduction in intraocular pressure (IOP) and in antiglaucoma medications in vitrectomized eyes in previously nonglaucomatous eyes. The most common indication for vitrectomy was ocular trauma-related complications.

PURPOSE

The purpose of this study was to report the long-term outcomes of AGV implantation in patients of uncontrolled IOP after pars plana vitrectomy (PPV).

MATERIALS AND METHODS

Medical records of patients (age 18 y and above) who underwent AGV implantation between January 2006 and December 2017 for uncontrolled IOP following PPV with ≥2 years follow-up were reviewed. The underlying etiology for PPV, IOP, best-corrected visual acuity, and number of antiglaucoma medications (AGMs) were recorded at baseline. The main outcomes measures were IOP, number of AGM, best-corrected visual acuity, and postoperative complications. Postoperative complications were classified as early (≤3 mo)/intermediate (>3 mo to ≤1 y), or late (>1 y).

RESULTS

In all, 78 eyes of 78 patients with a mean age of 38.06±17.83 years were included. The mean follow-up was 70.46±36.96 (range: 24 to 180) months. The main underlying etiology for PPV was trauma (38.4%) followed by rhegmatogenous retinal detachment (28.2%). The mean preoperative IOP was 29.33±9.84 mm Hg with an average of 4.07±1.2 AGM. The mean IOP and number of AGM was significantly reduced in all follow-up visits (P<0.0001) following AGV implantation. The cumulative probability of success was 92.3%, 80.7%, and 74% at 2, 5, and 10 years, respectively. Thirty-one complications were observed in 25 (32%) eyes and reoperation (23 procedures) was performed in 22 (28.2%) eyes.

CONCLUSIONS

AGV implantation had good outcome in patients with intractably elevated IOP following PPV. Trauma-related pathologies were a major contributor to the indications for PPV and had more chances of failure following AGV implantation.

摘要

目的

本研究旨在报告 Ahmed 青光眼阀(AGV)植入治疗接受过玻璃体切除术(PPV)后眼压(IOP)控制不佳的患者的长期结果。

材料和方法

回顾了 2006 年 1 月至 2017 年 12 月期间因 PPV 后 IOP 控制不佳且有≥2 年随访而接受 AGV 植入术的患者的病历。记录了基线时的潜在病因、IOP、最佳矫正视力和抗青光眼药物(AGM)数量。主要观察指标为 IOP、AGM 数量、最佳矫正视力和术后并发症。术后并发症分为早期(≤3 个月)/中期(>3 个月至≤1 年)和晚期(>1 年)。

结果

共纳入 78 例 78 只眼患者,平均年龄为 38.06±17.83 岁。平均随访时间为 70.46±36.96(范围:24 至 180)个月。PPV 的主要潜在病因是创伤(38.4%),其次是孔源性视网膜脱离(28.2%)。术前平均 IOP 为 29.33±9.84mmHg,平均使用 4.07±1.2 种 AGM。AGV 植入后所有随访时的平均 IOP 和 AGM 数量均显著降低(P<0.0001)。AGV 植入后 2、5 和 10 年的累积成功率分别为 92.3%、80.7%和 74%。25 只(32%)眼观察到 31 种并发症,22 只(28.2%)眼进行了 23 次再手术。

结论

AGV 植入术对接受过 PPV 治疗后眼压持续升高的患者有良好的疗效。与创伤相关的病变是导致行 PPV 的主要原因,并且在接受 AGV 植入后更有可能失败。

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